Скачать книгу - The Physiological Basis of Veterinary Clinical Pharmacology



The diversity of species in which drugs are used for clinical purposes and the emphasis on various classes of drugs make veterinary pharmacology a complex subject. Anatomical and physiological features influence the pharmacokinetic behaviour of a drug in a particular animal and the dosage required. This book is concerned with the basis of species differences, the selection of pharmacokinetic parameters and the interpretation of values obtained. There are chapters on bioavailability and its application to veterinary dosage forms, changes in drug disposition and interspecies scaling, clinical selectivity and stereoisomerism, drug permeation, antimicrobial disposition and specifics related to neonatal animals. The author has gathered all this information together in one place so allowing the reader to make better selection of drug preparations for animal dosages to effectively treat animal diseases. The book will prove valuable to clinical researchers in the areas of pharmacology, anaesthesia, microbial infections and, internal medicine as well as postgraduate students of these disciplines. The Author J Desmond Baggot (MVM, PhD, DSc, FRCVS, DipECVPT) is currently Visiting Professor of Veterinary Pharmacology at the School of Veterinary Medicine, St George's University, Grenada, West Indies. He was a contributing author and co-author of Antimicrobial Therapy in Veterinary Medicine, 3rd Edition (2000) and Development and Formulation of Veterinary Dosage Forms, 2nd Edition (1998) and the author of Principles of Drug Disposition in Domestic Animals (1977). Elucidations of the processes that underline species variation in the disposition of drugs and interpretation of the influence of disease states on drug disposition have been the focus of his research endeavours. He was a member of the Editorial Board of the Journal of Veterinary Pharmacology and Therapeutics from 1978 to 1996. He is a former Professor of Clinical Pharmacology at the School of Veterinary Medicine, University of California, Davis and Preclinical Veterinary Studies at the University of Zimbabwe, Harare.


Review. Benzene on the basis of the three-electron bond. Theory of three-electron bond in the four works with brief comments (review). 2016. Review. Benzene on the basis of the three-electron bond. Theory of three-electron bond in the four works with brief comments (review). 2016.

Автор: Volodymyr Bezverkhniy

Год издания: 

Using the concept of three-electron bond we can represent the actual electron structure of benzene and other molecules, explain specificity of the aromatic bond and calculate the delocalization energy. The aromatic bond is a three-electron bond in flat cyclic systems with a specific interaction of electrons through the cycle. In benzene formed a new type of chemical bonds – an aromatic bond, which has a multiplicity of more than 1.5 (1.66) http://vixra.org/author/bezverkhniy_volodymyr_dmytrovych


Project Management in Clinical Trials Project Management in Clinical Trials

Автор: Alexey Levashov

Год издания: 

The book is about both theoretical and practical aspects of Project Management in clinical trials. The audience may find explanation of different phenomena in modern clinical trials, for example, why some approaches in managing trials work and others – do not. In addition to this, the book should serve the purposes of business psychotherapy. The book is saturated with examples from real life and practical tips.


The Scientific Basis of National Progress, Including that of Morality The Scientific Basis of National Progress, Including that of Morality

Автор: Gore George

Год издания: 



What is time? How and on the basis of what it is formed? What is time? How and on the basis of what it is formed?

Автор: Юрий Михайлович Низовцев

Год издания: 

You want to learn, from where undertakes, for what and how your own "now" is formed? Read further, and to you the mystery of own life will be revealed. Still about it only guessed. Now, having come to the key, you will understand for what you live and as it is possible to change the life. No fantasy will be compared to the paradoxes of reality opened and provided here.


Clinical Nutrition For Dummies Clinical Nutrition For Dummies

Автор: Michael Rovito J.

Год издания: 

Get up to date on clinical nutrition for school, work, or your own health From the proper function of the major organs and the role that proper nutrition plays in their functioning, to a breakdown of carbs, proteins, fats, vitamins, and minerals, Clinical Nutrition For Dummies provides you with the easy-to-read guide you need to immerse yourself in the subject! Written in the fun style that the For Dummies series has become known for, the book is perfect for students in the wide variety of fields that require an in-depth understanding of clinical nutrition, or for those who want to improve their own lives through better nutrition. Dive right into the book for an exploration of the chemical and functional components of food, how to properly assess your nutritional intake, the changing face of nutrition throughout the human lifespan, and so much more! This handy resource offers a wealth of information, and specifically addresses the growing obesity and diabetes epidemics that promise to make the study of clinical nutrition more important than ever. Includes a complete breakdown of the relationship between nutrition and chronic diseases. Explores the nutritional requirements at various life stages, from pediatric through geriatric Features information on the importance of proper nutrition during pregnancy Shares tips for modifying dietary intake and health behavior theory, along with properly communicating health information Clinical Nutrition For Dummies is your complete, fun guide to the topic of nutrition—dive in today to get started on the pathway to mastering this increasingly important subject.