Найти книгу: "Lattice Boltzmann and Gas Kinetic Flux Solvers"

Computational fluid dynamics (CFD) has been widely applied in a wide variety of industrial applications, including aeronautics, astronautics, energy, chemical, pharmaceuticals, power and petroleum.This unique compendium documents the recent developments in CFD based on kinetic theories, introducing flux reconstruction strategies of kinetic methods for the simulation of complex incompressible and compressible flows, namely the lattice Boltzmann and the gas kinetic flux solvers (LBFS or GKFS). LBFS and GKFS combine advantages of both Navier-Stokes (N-S) solvers and kinetic solvers.Detailed derivations, evaluations and applications of LBFS and GKFS, and their advantages over conventional flux reconstruction strategies are analyzed and discussed in the volume.The must-have reference text is useful for scholars, researchers, professionals and students who are keen in CFD methods and numerical simulations.<b>Contents:</b> <ul><li>Introduction</li><li>Kinetic Equations</li><li>Lattice Boltzmann Flux Solver for Isothermal and Thermal Flows</li><li>Multiphase Lattice Boltzmann Flux Solver for Two-Phase Flows</li><li>Maxwellian Function-Based Gas Kinetic Flux Solver</li><li>Simplified Distribution Function-Based Gas Kinetic Flux Solvers</li><li>Discrete Gas Kinetic Flux Solvers</li><li>Gas Kinetic Flux Solvers for Incompressible Flows</li></ul><br><b>Readership:</b> Professionals, academics, researchers, and graduate students in mechanical engineering, aerospace engineering, engineering mechanics and mathematical physics. Finite Volume Method;Navier-Stokes Equations;Lattice Boltzmann Method;Gas Kinetic Scheme;Latice Boltzmann Flux Solver;Gas Kinetic Flux Solver00

Few scientists have the knowledge to perform the studies that are necessary to discover and characterize enzyme inhibitors, despite the vested interest the pharmaceutical industry has in this field. Beginning with the most basic principles pertaining to simple, one-substrate enzyme reactions and their inhibitors, and progressing to a thorough treatment of two-substrate enzymes, Kinetics of Enzyme Action: Essential Principles for Drug Hunters provides biochemists, medicinal chemists, and pharmaceutical scientists with numerous case study examples to outline the tools and techniques necessary to perform, understand, and interpret detailed kinetic studies for drug discovery.

This book is dedicated to the processes of mineral transformation, recycling and reclamation of metals, for the purpose of turning metals and alloys into a liquid state ready for pouring. Even though «process metallurgy» is one of the oldest technologies implemented by man, technological innovation, with the development of processes that are both focused on product quality and economically and ecologically efficient, continues to be at the heart of these industries. This book explains the physico-chemical bases of transformations, vital to their understanding and control (optimization of operational conditions), and the foundations in terms of «process engineering» (heat and matter assessment, process coupling: chemical reactions and transport phenomena), vital to the optimal execution and analysis of transformation process operations. This book is addressed to students in the field of metallurgy and to engineers facing the problem of metal and alloy development (operation of an industrial unit or development of a new process).

Rapid-Equilibrium Enzyme Kinetics helps readers emphasize the estimation of kinetic parameters with the minimum number of velocity measurements, thereby reducing the amount of laboratory work necessary, and allowing more time for the consideration of complicated mechanisms. The book systematically progresses through six levels of understanding the enzyme-catalyzed reaction, and includes a CD-ROM so that the reader may use the programs in the book to input their own experimental data.

Small structural modifications can significantly affect the pharmacokinetic properties of drug candidates. This book, written by a medicinal chemist for medicinal chemists, is a comprehensive guide to the pharmacokinetic impact of functional groups, the pharmacokinetic optimization of drug leads, and an exhaustive collection of pharmacokinetic data, arranged according to the structure of the drug, not its target or indication. The historical origins of most drug classes and general aspects of modern drug discovery and development are also discussed. The index contains all the drug names and synonyms to facilitate the location of any drug or functional group in the book. This compact working guide provides a wealth of information on the ways small structural modifications affect the pharmacokinetic properties of organic compounds, and offers plentiful, fact-based inspiration for the development of new drugs. This book is mainly aimed at medicinal chemists, but may also be of interest to graduate students in chemical or pharmaceutical sciences, preparing themselves for a job in the pharmaceutical industry, and to healthcare professionals in need of pharmacokinetic data.

The only book dedicated to physiologically-based pharmacokinetic modeling in pharmaceutical science Physiologically-based pharmacokinetic (PBPK) modeling has become increasingly widespread within the pharmaceutical industry over the last decade, but without one dedicated book that provides the information researchers need to learn these new techniques, its applications are severely limited. Describing the principles, methods, and applications of PBPK modeling as used in pharmaceutics, Physiologically-Based Pharmacokinetic (PBPK) Modeling and Simulations fills this void. Connecting theory with practice, the book explores the incredible potential of PBPK modeling for improving drug discovery and development. Comprised of two parts, the book first provides a detailed and systematic treatment of the principles behind physiological modeling of pharmacokinetic processes, inter-individual variability, and drug interactions for small molecule drugs and biologics. The second part looks in greater detail at the powerful applications of PBPK to drug research. Designed for a wide audience encompassing readers looking for a brief overview of the field as well as those who need more detail, the book includes a range of important learning aids. Featuring end-of-chapter keywords for easy reference—a valuable asset for general or novice readers without a PBPK background—along with an extensive bibliography for those looking for further information, Physiologically- Based Pharmacokinetic (PBPK) Modeling and Simulations is the essential single-volume text on one of the hottest topics in the pharmaceutical sciences today.