Найти книгу: "The Chemists' War"

Within months of the start of the First World War, Germany began to run out of the raw materials it needed to make explosives. As Germany faced imminent defeat, chemists such as Fritz Haber and Carl Bosch came to the rescue with Nobel Prize winning discoveries that overcame the shortages and enabled the country to continue in the war. Similarly, Britain could not have sustained its war effort for four years had it not been for chemists like Chaim Weizmann who was later to become the first president of the State of Israel. Michael Freemantle tells the stories of these and many other chemists and explains how their work underpinned and shaped what became known as The Chemists’ War. He reveals: • how chemistry contributed to the care of the sick and wounded and to the health and safety of troops; • how coal not only powered the war but was also an important source of the chemicals needed for the manufacture of explosives, dyes, medicines and antiseptics;• how Britain’s production of propellants relied on the slaughter of tens of thousands of whales;• how a precious metal played a critical role in the war;• how poisonous chemicals were used as weapons of mass destruction for the first time in the history of warfare and how chemists developed gas masks for protection against these weapons; • how the British naval blockade of Germany imperilled agricultural production in the United States. The book will appeal to the general reader as well as the many scientists and historians interested in the Great War.

Reviews from previous editions: «Excel for Chemists should be part of any academic library offering courses and programs in Chemistry.» —Choice «I highly recommend the book; treat yourself to it; assign it to a class; give it as a gift.» —The Nucleus The newly revised step-by-step guide to using the scientific calculating power of Excel to perform a variety of chemical calculations Chemists across all subdisciplines use Excel to record data in tabular form, but few have learned to take full advantage of the program. Featuring clear step-by-step instructions, Excel for Chemists illustrates how to use the scientific calculating power of Excel to perform a variety of chemical calculations. Including a CD-ROM for Windows, this new edition provides chemists and students with a detailed guide to using the current versions of Excel (Excel 2007 and 2010) as well as Excel 2003. Additional features in this third edition include: How to perform a variety of chemical calculations by creating advanced spreadsheet formulas or by using Excel’s built-in tools How to automate repetitive tasks by programming Excel’s Visual Basic for Applications New chapters show how to import data from other language versions of Excel, and how to create automatic procedures The accompanying CD contains a number of Excel macros to facilitate chemical calculations, including molecular weight, nonlinear regression statistics, and data interpolation Several appendices provide extensive lists of useful shortcut keys and function descriptions

Quantum Physics for Scientists and Technologists is a self-contained, comprehensive review of this complex branch of science. The book demystifies difficult concepts and views the subject through non-physics fields such as computer science, biology, chemistry, and nanotechnology. It explains key concepts and phenomena in the language of non-physics majors and with simple math, assuming no prior knowledge of the topic. This cohesive book begins with the wavefunction to develop the basic principles of quantum mechanics such as the uncertainty principle and wave-particle duality. Comprehensive coverage of quantum theory is presented, supported by experimental results and explained through applications and examples without the use of abstract and complex mathematical tools or formalisms. From there, the book: Takes the mystery out of the Schrodinger equation, the fundamental equation of quantum physics, by applying it to atoms Shows how quantum mechanics explains the periodic table of elements Introduces the quantum mechanical concept of spin and spin quantum number, along with Pauli's Exclusion Principle regarding the occupation of quantum states Addresses quantum states of molecules in terms of rotation and vibration of diatomic molecules Explores the interface between classical statistical mechanics and quantum statistical mechanics Discusses quantum mechanics as a common thread through different fields of nanoscience and nanotechnology Each chapter features real-world applications of one or more quantum mechanics principles. «Study Checkpoints» and problems with solutions are presented throughout to make difficult concepts easy to understand. In addition, pictures, tables, and diagrams with full explanations are used to present data and further explain difficult concepts. This book is designed as a complete course in quantum mechanics for senior undergraduates and first-year graduate students in non-physics majors. It also applies to courses such as modern physics, physical chemistry and nanotechnology. The material is also accessible to scientists, engineers, and technologists working in the fields of computer science, biology, chemistry, engineering, and nanotechnology.

Helps you choose the right computational tools and techniques to meet your drug design goals Computational Drug Design covers all of the major computational drug design techniques in use today, focusing on the process that pharmaceutical chemists employ to design a new drug molecule. The discussions of which computational tools to use and when and how to use them are all based on typical pharmaceutical industry drug design processes. Following an introduction, the book is divided into three parts: Part One, The Drug Design Process, sets forth a variety of design processes suitable for a number of different drug development scenarios and drug targets. The author demonstrates how computational techniques are typically used during the design process, helping readers choose the best computational tools to meet their goals. Part Two, Computational Tools and Techniques, offers a series of chapters, each one dedicated to a single computational technique. Readers discover the strengths and weaknesses of each technique. Moreover, the book tabulates comparative accuracy studies, giving readers an unbiased comparison of all the available techniques. Part Three, Related Topics, addresses new, emerging, and complementary technologies, including bioinformatics, simulations at the cellular and organ level, synthesis route prediction, proteomics, and prodrug approaches. The book's accompanying CD-ROM, a special feature, offers graphics of the molecular structures and dynamic reactions discussed in the book as well as demos from computational drug design software companies. Computational Drug Design is ideal for both students and professionals in drug design, helping them choose and take full advantage of the best computational tools available. Note: CD-ROM/DVD and other supplementary materials are not included as part of eBook file.

Small structural modifications can significantly affect the pharmacokinetic properties of drug candidates. This book, written by a medicinal chemist for medicinal chemists, is a comprehensive guide to the pharmacokinetic impact of functional groups, the pharmacokinetic optimization of drug leads, and an exhaustive collection of pharmacokinetic data, arranged according to the structure of the drug, not its target or indication. The historical origins of most drug classes and general aspects of modern drug discovery and development are also discussed. The index contains all the drug names and synonyms to facilitate the location of any drug or functional group in the book. This compact working guide provides a wealth of information on the ways small structural modifications affect the pharmacokinetic properties of organic compounds, and offers plentiful, fact-based inspiration for the development of new drugs. This book is mainly aimed at medicinal chemists, but may also be of interest to graduate students in chemical or pharmaceutical sciences, preparing themselves for a job in the pharmaceutical industry, and to healthcare professionals in need of pharmacokinetic data.

This book guides medicinal chemists in how to implement early ADMET testing in their workflow in order to improve both the speed and efficiency of their efforts. Although many pharmaceutical companies have dedicated groups directly interfacing with drug discovery, the scientific principles and strategies are practiced in a variety of different ways. This book answers the need to regularize the drug discovery interface; it defines and reviews the field of ADME for medicinal chemists. In addition, the scientific principles and the tools utilized by ADME scientists in a discovery setting, as applied to medicinal chemistry and structure modification to improve drug-like properties of drug candidates, are examined.