The Misuse of Drugs Act
Автор: Leslie A King
Год издания: 0000
In recent years, the use of illegal substances has increased, particularly 'designer' drugs which have rapidly become part of youth culture. The need for all involved in drug control to have up to date information about the subject has never been greater. This book helps meet this need by providing a chemical background to the legal controls on drugs of abuse. Although focussed on the UK, some of the provisions of the Misuse of Drugs Act derive from international treaties; the discussion of technical aspects is therefore of wider relevance. Apart from the Act itself, the book also deals with certain aspects of the Misuse of Drugs Regulations. There is detailed coverage of 'designer drugs' and the generic legislation that was introduced to tackle them. The more recent addition of 35 'Ecstasy'-like substances is covered in depth. The significance to the legislation of terms such as salt, base, stereoisomer, ester, ether, derivative, homologue and isotope are described, and the text is supplemented by 23 Tables and over 80 chemical structures. There are eleven Appendices covering topics such as precursor chemicals, related legislation, stated cases, sentencing guidelines and the chemical characteristics of commonly-abused drugs. Up-to-date lists of controlled drugs, with cross references to their status in UN treaties, are provided and a number of pending and other possible changes to the Act are included together with a guide to nomenclature and synonyms. Although primarily aimed at forensic scientists, this book will be of great benefit to all bodies concerned with drug control, including the police, customs officers, lawyers and government departments.
27 Club. How the idols were dying. Sex, drugs and rock and roll
Автор: Jim Jones
Год издания:
Forever young musicians. Full list and rare facts. The list of «27 Club» is not limited to Amy Winehouse and Jim Morrison. In this unusual club more than 40 names! Richie Edwards, Dmitry Chekov, Alexander Korzhov, Mia Katherine Zapata, Igor Chumychkin, Pete da Freitas and many others! So talented, so young. What other beautiful music could they give the world if they did not leave so early?
Bad Medicine. Misconceptions and Misuses Revealed, from Distance Healing to Vitamin O
Автор: Christopher Wanjek
Год издания:
"Christopher Wanjek uses a take-no-prisoners approach in debunking the outrageous nonsense being heaped on a gullible public in the name of science and medicine. Wanjek writes with clarity, humor, and humanity, and simultaneously informs and entertains." -Dr. Michael Shermer, Publisher, Skeptic magazine; monthly columnist, Scientific American; author of Why People Believe Weird Things Prehistoric humans believed cedar ashes and incantations could cure a head injury. Ancient Egyptians believed the heart was the center of thought, the liver produced blood, and the brain cooled the body. The ancient Greek physician Hippocrates was a big fan of bloodletting. Today, we are still plagued by countless medical myths and misconceptions. Bad Medicine sets the record straight by debunking widely held yet incorrect notions of how the body works, from cold cures to vaccination fears. Clear, accessible, and highly entertaining, Bad Medicine dispels such medical convictions as: * You only use 10% of your brain: CAT, PET, and MRI scans all prove that there are no inactive regions of the brain . . . not even during sleep. * Sitting too close to the TV causes nearsightedness: Your mother was wrong. Most likely, an already nearsighted child sits close to see better. * Eating junk food will make your face break out: Acne is caused by dead skin cells, hormones, and bacteria, not from a pizza with everything on it. * If you don't dress warmly, you'll catch a cold: Cold viruses are the true and only cause of colds. Protect yourself and the ones you love from bad medicine-the brain you save may be your own.
Inside the FDA. The Business and Politics Behind the Drugs We Take and the Food We Eat
Автор: Fran Hawthorne
Год издания:
The forces that shape America's most powerful consumer agency Because of the importance of what it regulates, the FDA comes under tremendous political, industry, and consumer pressure. But the pressure goes far beyond the ordinary lobbying of Washington trade groups. Its mandate-one quarter of the national economy-brings the FDA into the middle of some of the most important and contentious issues of modern society. From «designer» babies and abortion to the price of prescription drugs and the role of government itself, Inside the FDA takes readers on an intriguing journey into the world of today's most powerful consumer agency. In a time when companies continue to accuse the FDA of nitpicking and needlessly delaying needed new drugs, and consumers are convinced that the agency bends to industry pressure by rushing unsafe drugs to market, Inside the FDA digs deep to reveal the truth. Through scores of interviews and real-world stories, Hawthorne also shows how and why the agency makes some of its most controversial decisions as well as how its recent reaction to certain issues-including the revolutionary cancer drug Erbitux, stem cell research, and bioengineering of food-may jeopardize its ability to keep up with future scientific developments. Inside the FDA takes a closer look at the practices, people, and politics of this crucial watchdog in light of the competing pressures and trends of modern society, revealing what the FDA is supposed to do, what it actually does-and fails to do-who it influences, and how it could better fulfill its mandate. The decisions that the FDA makes are literally life and death. Inside the FDA provides a sophisticated account of how this vitally important agency struggles to balance bureaucracy and politics with its overriding mission to promote the country's health.
Antiviral Drugs. From Basic Discovery Through Clinical Trials
Автор: Wieslaw Kazmierski M.
Год издания:
This book focuses on new small molecule approaches to combat viral infections. The chapters describe the discovery and development from bench through the clinic of relatively recently-approved antiviral drugs and compounds in advanced clinical development. Organized by a virus (such as HIV, HCV, RSV, influenza, HBV and CMV) and written by top academic and industrial authorities in the field, the book provides a unique opportunity to study, understand and apply discovery and development principles and learning without the need for an individual to research, analyze and synthesize all immense sourcing references. Topics showcase challenges and solutions of issues encountered, offering tremendous experience accumulated over many years of research that will be particularly useful to basic and bench scientists as well as clinicians as they continue discovering and developing new drugs and therapies.
The Use and Misuse of Psychiatric Drugs. An Evidence-Based Critique
Автор: Joel Paris
Год издания:
Dr. Paris has written an honest, balanced presentation of the ways in which psychiatric drugs are evaluated and prescribed. He highlights the complexity of the task, the limits of what is known and the mixed picture that research often produces. His conclusions are refreshing because they are built from an even-handed, pragmatic assessment of the empirical evidence. The result is a stimulating look at the world of treatments for emotional disorders that acknowledges the usefulness of both biological and psychosocial explanations where appropriate. His recommendations provide helpful roadmaps for patients, practitioners and researchers alike. The book is sure to serve as a welcome catalyst for the continuing debates about which treatments are likely to produce the best outcomes. —Roger P. Greenberg, Ph.D. Distinguished Professor and Head, Psychology Division Dept. of Psychiatry & Behavioral Science SUNY Upstate Medical University, NY, USA The message of this book is that psychiatrists have some very good drugs, but can expect bad results when they are over-used, prescribed outside of evidence-based indications, or given to the wrong patients. While acknowledging that many current agents are highly effective and have revolutionized the treatment of certain disorders, Joel Paris criticizes their use outside of an evidence base. Too many patients are either over-medicated or are misdiagnosed to justify aggressive treatment. Dr. Paris calls for more government funding of clinical trials to establish, without bias, the effectiveness of these agents. He has written this book for practitioners and trainees to show that scientific evidence supports a more cautious and conservative approach to drug therapy. After describing the history of psychopharmacology, including its early successes, Dr. Paris reviews the relationship between psychiatry and the pharmaceutical industry. This problem has received considerable popular attention in recent years and Dr. Paris documents initiatives to increase transparency and decrease the influence of pharmaceutical marketing on diagnosis and prescribing habits. Dr Paris then examines some major controversies. One is the fact that newer drugs have not been shown to be superior to older agents. Another is that while the number of prescriptions for antidepressants has increased dramatically, meta-analyses show that their value is more limited than previously believed. Still another is the widespread prescription of mood stabilizers and antipsychotic drugs for patients, including children and adolescents, who do not have bipolar illness. Polypharmacy is an especially contentious area: very few drug combinations have been tested in clinical trials, yet many patients end up on a cocktail of powerful drugs, each with its own side effects. Dr Paris briefly considers alternatives to pharmacology and again calls for more clinical trials of these approaches. He also discusses the current trend to medicalizing what many would describe as normal distress and states succinctly: Some things in life are worth being upset about.