Найти книгу: "Integration of Omics Approaches and Systems Biology for Clinical Applications"

Introduces readers to the state of the art of omics platforms and all aspects of omics approaches for clinical applications This book presents different high throughput omics platforms used to analyze tissue, plasma, and urine. The reader is introduced to state of the art analytical approaches (sample preparation and instrumentation) related to proteomics, peptidomics, transcriptomics, and metabolomics. In addition, the book highlights innovative approaches using bioinformatics, urine miRNAs, and MALDI tissue imaging in the context of clinical applications. Particular emphasis is put on integration of data generated from these different platforms in order to uncover the molecular landscape of diseases. The relevance of each approach to the clinical setting is explained and future applications for patient monitoring or treatment are discussed. Integration of omics Approaches and Systems Biology for Clinical Applications presents an overview of state of the art omics techniques. These methods are employed in order to obtain the comprehensive molecular profile of biological specimens. In addition, computational tools are used for organizing and integrating these multi-source data towards developing molecular models that reflect the pathophysiology of diseases. Investigation of chronic kidney disease (CKD) and bladder cancer are used as test cases. These represent multi-factorial, highly heterogeneous diseases, and are among the most significant health issues in developed countries with a rapidly aging population. The book presents novel insights on CKD and bladder cancer obtained by omics data integration as an example of the application of systems biology in the clinical setting. Describes a range of state of the art omics analytical platforms Covers all aspects of the systems biology approach—from sample preparation to data integration and bioinformatics analysis Contains specific examples of omics methods applied in the investigation of human diseases (Chronic Kidney Disease, Bladder Cancer) Integration of omics Approaches and Systems Biology for Clinical Applications will appeal to a wide spectrum of scientists including biologists, biotechnologists, biochemists, biophysicists, and bioinformaticians working on the different molecular platforms. It is also an excellent text for students interested in these fields.

The personal home page (PHP) server-side scripting language is particular well adapted to connecting HTML-based web pages to a backend database for dynamic content. This book explains the entire nuts-and-bolts process of the PHP application life cycle: requirements, design, development, maintenance and tuning. It shows how PHP can be used to design and develop highly manageable and secure applications to solve practical problems.

Written by members of the Oracle XML group, this is a must-have reference for all IT managers, DBAs, and developers who want to learn the best practices for using XML with Oracle’s XML-enabled products. Includes real-world case studies based on theauthors’ experience managing Oracle’s XML Discussion Forum - a community of 20,000+ XML component users.

This book will serve as an ideal guide to the relatively new and complex field of bioelectromagnetics for students and researchers interested in the interaction of biological systems and electromagnetic fields. Coverage details:(1) biological responses of human and animals, both in vivo and in vitro methodologies, to magnetic and/or electromagnetic field exposure, (2) characteristics of effective fields, (3) hypotheses to explain possible mechanisms of interaction between the fields and cells, and (4) induced current in ELF and induced heat in RF fields as key interaction mechanisms.

Rizzoni is designed for the sophomore/junior level, Introduction to Electrical Engineering course required for non-EE majors. The most widely used book for this course, Rizzoni introduces non-majors to the three basic areas of electrical engineering: circuits, electronics, and electromechanics. The second edition continues the tradition of focusing on the topics and issues of interest to the non-electrical engineering student. To maintain student interest in these topics, Rizzoni provides numerous links between electrical engineering and other engineering fields.

В книге содержится описание прикладной программы Simulink и библиотеки блоков SimPowerSystems, предназначенной для моделирования электротехнических устройств и систем. Рассматривается методика создания моделей с помощью графического интерфейса программы, описаны методы расчета моделей, подробно освещена методика создания электротехнических блоков пользователя. Даны основные команды для управления моделью из ядра пакета MATLAB, рассмотрен механизм выполнения расчета модели, приводятся советы автора по применению программы. Книга включает в себя большое количество примеров, поясняющих работу блоков и методику создания модели.