Найти книгу: "Polypeptide Hormones"

The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.

Many small molecules occur naturally as «messenger» chemicals which regulate the behaviour and functions of microbes, plants, insects and animals. Examples include hormones, pheromones, phytoalexins, and antifeedants. These biofunctional molecules are of great interest to researchers in helping develop our understanding of biological function and in the development of new drugs. However extracting them from nature can be prohibitively expensive, so there is great interest in devising methods of synthesising them from simple starting materials in the laboratory. Chemical Synthesis of Hormones, Pheromones and Other Bioregulators is an introduction to the techniques and strategies for the synthesis of biofunctional small molecules. Topics include: what are biofunctional molecules? why must biofunctional molecules be synthesized? how can we synthesize biofunctional molecules? the synthesis of phytohormones, phytoalexins and other biofunctional molecules of plant origin the synthesis of insect juvenile hormones and antifeedants the synthesis of pheromones and the significance of chirality in pheromone science the synthesis of microbial hormones and pheromones, antibiotics, and other biofunctional molecules of microbial origin the synthesis of marine antifeedants and medicinal candidates a synthetic examination of incorrectly proposed structures of biomolecules reflections on science as a human endeavor Drawing on a career of almost 50 years researching and teaching this subject, Kenji Mori's Chemical Synthesis of Hormones, Pheromones and Other Bioregulators is a must-have textbook for students and researchers of organic synthesis and natural products, and a stimulating and inspiring account of a distinguished chemical career.

As life expectancy increases and population ages, the already enormous impact of neurodegeneration on society will become even larger without better prevention and treatment. Developing strategies to prevent degeneration of neurons and to promote a healthy nervous system is, thus, critical. The development of pharmacological agents that would increase production of new neurons was recently facilitated by the identification of the hormonal regulators of various steps of adult neurogenesis. The proposed book is writen by a group of top world experts involved in the study of the mechanisms of hormonal control of brain damage and repair. The effects of thyroid and steroid hormones (estrogens, androgens, progestins, gluco-mineralo-corticoids, various neurosteroids) or polypeptide hormones (CRF, urocortins, somatostastin, GH/IGF, leptin, prolactin, PACAP, erythropoetin) on neuronal survival and neurogenesis in various neurodegenerative conditions and in brain aging will be discussed in detail. The proposed book is unique because it gives a comprehensive account of the neuroprotective and neurogenic effects of steroid and polypeptide hormones. Furthermore, new pharmacological approaches for treatment of neurodegenerative conditions are presented, based on the neuroprotective and neurogenic properties of natural and synthetic hormones.

Women over the age of 40, as they move towards menopause, usually experience an increasing waistline and multiplying fat cells…no matter how much they exercise.Hormonal changes start to affect your weight when your 30 billion fat cells detect a slightly lower oestrogen reading and come to your aid to produce oestrogen for you. And the fat cells in your waist grow the largest because they are better equipped to produce oestrogen than those in your bottom, hips and thighs.Debra Waterhouse provides her usual sound strategies to cope but also explains the positive side: that the more oestrogen you produce the fewer mood swings and hot flushes, less intense PMS, improved sleep, and a reduced risk of osteoporosis you will experience. And she warns: the harder you try to lose weight by dieting the more powerful your menopausal fat cells become .Positive actions Waterhouse proposes include:• Encouraging a positive attitude for your change of life, embracing your body changes• Following her tailored exercise programme which includes building bone density and gaining muscle• How much to eat, when and how often. What to eat, including plant oestrogens. And how to start trusting your body’s messages and cravings.

I Blame the Hormones follows the story of one woman battling long-term depression, her determination to root out the cause, and her ultimate discovery which freed her from its prison.Caroline Church suffered from a depression so chronic she experienced hallucinations, delusions and even suicidal inclinations. Yet through exploring the correlation between her depressive episodes and the basic elements of female nature, over many years she discovered that what she thought was a mental disorder was actually due to a hormonal imbalance. And the best bit? She learnt what she could do and take to control it.Shocking, vivid, and a must read for women, their partners and healthcare professionals alike, I Blame the Hormones is the uplifting memoir of Caroline’s journey to pull herself through despite all the odds.