Найти книгу: "Pharmacophores and Pharmacophore Searches"

This handbook is the first to address the practical aspects of this novel method. It provides a complete overview of the field and progresses from general considerations to real life scenarios in drug discovery research. Starting with an introductory historical overview, the authors move on to discuss ligand-based approaches, including 3D pharmacophores and 4D QSAR, as well as the concept and application of pseudoreceptors. The next section on structure-based approaches includes pharmcophores from ligand-protein complexes, FLIP and 3D protein-ligand binding interactions. The whole is rounded off with a complete section devoted to applications and examples, including modeling of ADME properties. With its critical evaluation of pharmacophore-based strategies, this book represents a valuable aid for project leaders and decision-makers in the pharmaceutical industry, as well as pharmacologists, and medicinal and chemists.

Полный вариант заголовка: «Researches in the highlands of Turkey : including visits to mounts Ida, Athos, Olympus, and Pelion, to the Mirdite Albanians, and other remote tribes: with notes on the ballads tales, and classical superstitions of the modern Greeks : in 2 vol. T. 4. L'Economie rurale de Columella».

Полный вариант заголовка: «Asiatic researches : Vol. 1 : or, transactions of the society instituted in Bengal, for inquiring into the history and antiquities, the arts, sciences, and literature, of Asia / printed verbatim from the Calcutta edition».

Полный вариант заголовка: «Asiatic researches : Vol. 2 : or, transactions of the society instituted in Bengal, for inquiring into the history and antiquities, the arts, sciences, and literature, of Asia / printed verbatim from the Calcutta edition.».

Полный вариант заголовка: «Asiatick researches : Vol. 3 : or, transactions of the society instituted in Bengal, for inquiring into the history and antiquities, the arts, sciences, and literature, of Asia / printed verbatim from the Calcutta edition.».

Полный вариант заголовка: «Asiatick researches : Vol. 4 : or, transactions of the society instituted in Bengal, for inquiring into the history and antiquities, the arts, sciences, and literature, of Asia / printed verbatim from the Calcutta edition, in Quarto».