Molecular Epidemiology of Chronic Diseases
Автор: Chris Wild
Год издания: 0000
I think this is an excellent book–I recommend it to anyone involved in molecular epidemiology… The 26 chapters are written by topic specialists, in an explanatory, east to read style. –BTS Newsletter, Summer 2009 «This text provides an accessible and useful handbook for the epidemiologist who wants to survey the field, to become better informed, to look at recent developments and get some background on these or simply to appreciate further the relatively rapid changes in informatic and analytical technologies which increasingly will serve and underpin future epidemiological studies. One of the strengths in this book is the extensive array of practical illustrative examples, and it would also in my opinion have useful potential as a teaching text.» –American Journal of Human Biology, March 2009 With the sequencing of the human genome and the mapping of millions of single nucleotide polymorphisms, epidemiology has moved into the molecular domain. Scientists can now use molecular markers to track disease-associated genes in populations, enabling them to study complex chronic diseases that might result from the weak interactions of many genes with the environment. Use of these laboratory generated biomarker data and an understanding of disease mechanisms are increasingly important in elucidating disease aetiology. Molecular Epidemiology of Disease crosses the disciplinary boundaries between laboratory scientists, epidemiologists, clinical researchers and biostatisticians and is accessible to all these relevant research communities in focusing on practical issues of application, rather than reviews of current areas of research. Covers categories of biomarkers of exposure, susceptibility and disease Includes chapters on novel technologies: genomics, transcriptomics, proteomics and metabonomics, which are increasingly finding application in population studies Emphasizes new statistical and bioinformatics approaches necessitated by the large data sets generated using these new methodologies Demonstrates the potential applications of laboratory techniques in tackling epidemiological problems while considering their limitations, including the sources of uncertainty and inaccuracy Discusses issues such as reliability (compared to traditional epidemiological methods) and the timing of exposure Explores practical elements of conducting population studies, including biological repositories and ethics Molecular Epidemiology of Disease provides an easy-to-use, clearly presented handbook that allows epidemiologists to understand the specifics of research involving biomarkers, and laboratory scientists to understand the main issues of epidemiological study design and analysis. It also provides a useful tool for courses on molecular epidemiology, using many examples from population studies to illustrate key concepts and principles.
Chronica Nestoris
Автор: Fr. Miklosich
Год издания:
Приведен оригинальный текст Повести временных лет и краткая характеристика его на латинском языке.
Chronicon preciosum
Автор: Группа авторов
Год издания:
Полный вариант заголовка: «Chronicon preciosum : or an account of English money, the price of corn, and other commodities, for the last 600 years : in a letter to a student in the University of Oxford».
An account of a successful method of treating diseases of the spine
Автор: Thomas Baynton
Год издания:
Полный вариант заголовка: «An account of a successful method of treating diseases of the spine : With observations, and cases in illustration / By Thomas Baynton».
Synchronicity. The Inner Path of Leadership
Автор: Joseph Jaworski
Год издания:
We’ve all had those perfect moments when events that could never be predicted, let alone controlled, remarkably seem to guide us along our path. Carl Jung called this phenomena “synchronicity” – “a collaboration between persons and events that seems to enlist the cooperation of fate.” In this book, Joseph Jaworski argues that the right state of mind will make you the kind of person who can enlist the cooperation of fate and take advantage of synchronicity, creating the conditions for “predictable miracles.” If you are tired of being the victim of circumstances, this book will teach you to be the kind of person who creates your own circumstances. Jaworski shares the story of his own escape from an inauthentic life and his journey into a world filled with possibility. He maps out the inner path of leadership for those who feel the call to achieve their full potential, using his own life story to teach readers a greater truth. He examines the fundamental shifts of mind that free us to seek out the power of synchronicity. After reading this book, you will discover your own power to help those realities unfold. You will learn to “listen” to realities that want to emerge in this world and acquire the courage to help them be born. "Synchronicity illustrates that leadership is about the release of human possibilities, about enabling others to break free of limits – created organizationally or self-imposed. Although this book describes the author's personal journey, it contains profound messages about organizational learning and effectiveness." – Scientific American