Найти книгу: "Purinergic Signalling in Neuron-Glia Interactions"

ATP, the intracellular energy source, is also an extremely important cell–cell signalling molecule for a wide variety of cells across evolutionarily diverse organisms. The extracellular biochemistry of ATP and its derivatives is complex, and the multiple membrane receptors that it activates are linked to many intracellular signalling systems. Purinergic signalling affects a diverse range of cellular phenomena, including ion channel function, cytoskeletal dynamics, gene expression, secretion, cell proliferation, differentiation and cell death. Recently, this class of signalling molecules and receptors has been found to mediate communication between neurons and non-neuronal cells (glia) in the central and peripheral nervous systems. Glia are critical for normal brain function, development and response to injury. Neural impulse activity is detected by glia and purinergic signalling is emerging as a major means of integrating functional activity between neurons, glia and vascular cells in the nervous system. These interactions mediate effects of neural activity on the development of the nervous system and in association with injury, neurodegeneration, myelination and cancer. Bringing together contributions from experts in diverse fields, including glial biologists, neurobiologists and specialists in purinergic receptor structure and pharmacology, this book considers how extracellular ATP acts to integrate communication between different types of glia, and between neurons and glia. Beginning with an overview of glia and purinergic signalling, it contains detailed coverage of purine release, receptors and reagents, purinergic signalling in the neural control of glial development, glial involvement in information processing, and discussion of the interactions between neurons and microglia.

Plants interact with a wide variety of organisms in their natural growing environments. Key amongst these relationships is the interplay between plants and diverse fungal species that impact plants in complex symbiotic, parasitic and pathogenic ways. Biocomplexity of Plant-Fungal Interactions explores a broad spectrum of research looking at both positive and negative interactions of these relationships on plants and their ecosystems. Biocomplexity of Plant-Fungal Interactions takes a more holistic view of the plant-fungal interactions than most traditional volumes on the topic. Focusing on the truly complex biological interplay among plants and fungi, as well as other organisms—mammals, insects, bacteria, viruses, this book provides a unique perspective on this fundamentally important relationship. Chapters are written from molecular, evolutionary and ecological perspectives to provide readers with a full understanding of the diverse implications of plant-fungal interactions. Written by a global team of experts from varied scientific backgrounds, Biocomplexity of Plant-Fungal Interactions will be an essential title for readers looking for a better understanding of the diverse array of interactions between plants and fungi in natural ecosystems.

Fully integrated and comprehensive in its coverage, Root Genomics and Soil Interactions examines the use of genome-based technologies to understand root development and adaptability to biotic and abiotic stresses and changes in the soil environment. Written by an international team of experts in the field, this timely review highlights both model organisms and important agronomic crops. Coverage includes: novel areas unveiled by genomics research basic root biology and genomic approaches applied to analysis of root responses to the soil environment. Each chapter provides a succinct yet thorough review of research.

The human-computer interactions are more and more present in our everyday life, and lead to many conceptual and methodological problems for the designers and evaluators of interactive systems. This book is about Human-Computer Interaction in Transport domain, in which the traveler becomes a user of information systems, particularly before and during the travel(s). This book will focus on traveler information and personalized systems, using a human-centered design approach.

Annual Plant Reviews, Volume 11 Plant diseases are destructive and threaten virtually any crop grown on a commercial scale. They are kept in check by plant breeding strategies that have introgressed disease resistance genes into many important crops, and by the deployment of costly control measures, such as antibiotics and fungicides. However, the capacity for the agents of plant disease – viruses, bacteria, fungi and oomycetes – to adapt to new conditions, overcoming disease resistance and becoming resistant to pesticides, is very great. For these reasons, understanding the biology of plant diseases is essential for the development of durable control strategies. This volume provides an overview of our current knowledge of plant-pathogen interactions and the establishment of plant disease, drawing together fundamental new information on plant infection mechanisms and host responses. The role of molecular signals, gene regulation and the physiology of pathogenic organisms are emphasised, but the role of the prevailing environment in the conditioning of disease is also discussed. This is a book for researchers and professionals in plant pathology, cell biology, molecular biology and genetics.

Crystal engineers aim to control the way molecules aggregate in the crystalline phase and are therefore concerned with crystal structure prediction, polymorphism, and discovering the relative importance of different types of intermolecular forces and their influence on molecular structure. In order to design crystal structures, knowledge of the types, strengths, and nature of possible intermolecular interactions is essential. Non-covalent interactions involving p-systems is a theme that is under extensive investigation as these interactions can be inductors for the assembly of a vast array of supramolecular architectures. The Importance of Pi-Interactions in Crystal Engineeringcovers topics ranging from the identification of interactions involving p-systems, their impact on molecular and crystal structure in both organic and metallorganic systems, and how these interactions might be exploited in the design of new materials. Specialist reviews are written by internationally recognized researchers drawn from both academia and industry. The Importance of Pi-Interactions in Crystal Engineeringprovides an essential overview of this important aspect of crystal engineering for both entrants to the field as well as established practitioners, and for those working in crystallography, medicinal and pharmaceutical sciences, solid-state chemistry, physical chemistry, materials and nanotechnology