Найти книгу: "An Introduction to Statistics in Early Phase Trials"

All new medicines and devices undergo early phase trials to assess, interpret and better understand their efficacy, tolerability and safety. An Introduction to Statistics in Early Phase Trials describes the practical design and analysis of these important early phase clinical trials and provides the crucial statistical basis for their interpretation. It clearly and concisely provides an overview of the most common types of trials undertaken in early phase clinical research and explains the different methodologies used. The impact of statistical technologies on clinical development and the statistical and methodological basis for making clinical and investment decisions are also explained. Conveys key ideas in a concise manner understandable by non-statisticians Explains how to optimise designs in a constrained or fixed resource setting Discusses decision making criteria at the end of Phase II trials Highlights practical day-to-day issues and reporting of early phase trials An Introduction to Statistics in Early Phase Trials is an essential guide for all researchers working in early phase clinical trial development, from clinical pharmacologists and pharmacokineticists through to clinical investigators and medical statisticians. It is also a valuable reference for teachers and students of pharmaceutical medicine learning about the design and analysis of clinical trials.

This book is intended to provide the applied researcher with the capacity to perform statistical analyses with SAS software without wading through pages of technical documentation. The researcher is provided with the necessary SAS statements to run programs for most of the commonly used statistics, explanations of the computer output, interpretations of results, and examples of how to construct tables and write up results for reports and journal articles.

Полный вариант заголовка: «Introduction a la philosophie, contenant la metaphysique et la logique / par G.J. 's Gravesande ; traduite du latin ; nouvelle edition revue, corrigee, et augmentee de l'art de raisonner par syllogismes».

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