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Combating the Threat of Pandemic Influenza Combating the Threat of Pandemic Influenza

Автор: Группа авторов

Год издания: 0000

Drug discovery for influenza antivirals Priorities for combating pandemic influenza include rapid detection and identification, the quick administration of available drugs to treat the infection, the development of new antivirals, and the development of vaccines. Since lead-time may be required to produce an effective vaccine, antivirals would serve as a key first line of defense in containing an outbreak. Diverse antivirals, acting through different mechanisms, would help stay the development of resistant viruses. Thus, drug discovery for influenza antivirals is an important public health-related endeavor. With chapters contributed by leading international specialists, this guide gets readers up to speed on the latest advances and technologies in diverse approaches to drug discovery, covering: * Existing antivirals, including broadly effective anti-respiratory virus agents * The development of high-throughput screening assays * IFN resistance * The development of nucleic acid-based antiviral drugs * Antiviral RNAi strategies targeting influenza virus * Other promising antiviral drug discovery strategies Combating the Threat of Pandemic Influenza: Drug Discovery Approaches consolidates the latest information on diverse approaches into one comprehensive resource. It is an invaluable, hands-on reference for researchers in medicinal chemistry, pharmaceutical chemistry, drug discovery, biochemistry, virology, microbiology, and public health.
Influenza. Лирика Influenza. Лирика

Автор: Анатолий Жариков

Год издания: 

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Cyber Threat!. How to Manage the Growing Risk of Cyber Attacks Cyber Threat!. How to Manage the Growing Risk of Cyber Attacks

Автор: MacDonnell Ulsch

Год издания: 

Conquering cyber attacks requires a multi-sector, multi-modal approach Cyber Threat! How to Manage the Growing Risk of Cyber Attacks is an in-depth examination of the very real cyber security risks facing all facets of government and industry, and the various factors that must align to maintain information integrity. Written by one of the nation's most highly respected cyber risk analysts, the book describes how businesses and government agencies must protect their most valuable assets to avoid potentially catastrophic consequences. Much more than just cyber security, the necessary solutions require government and industry to work cooperatively and intelligently. This resource reveals the extent of the problem, and provides a plan to change course and better manage and protect critical information. Recent news surrounding cyber hacking operations show how intellectual property theft is now a matter of national security, as well as economic and commercial security. Consequences are far-reaching, and can have enormous effects on national economies and international relations. Aggressive cyber forces in China, Russia, Eastern Europe and elsewhere, the rise of global organized criminal networks, and inattention to vulnerabilities throughout critical infrastructures converge to represent an abundantly clear threat. Managing the threat and keeping information safe is now a top priority for global businesses and government agencies. Cyber Threat! breaks the issue down into real terms, and proposes an approach to effective defense. Topics include: The information at risk The true extent of the threat The potential consequences across sectors The multifaceted approach to defense The growing cyber threat is fundamentally changing the nation's economic, diplomatic, military, and intelligence operations, and will extend into future technological, scientific, and geopolitical influence. The only effective solution will be expansive and complex, encompassing every facet of government and industry. Cyber Threat! details the situation at hand, and provides the information that can help keep the nation safe.

Financial Contagion. The Viral Threat to the Wealth of Nations Financial Contagion. The Viral Threat to the Wealth of Nations

Автор: Robert Kolb W.

Год издания: 

Financial Contagion: The Viral Threat to the Wealth of Nations covers a lot of territory. It is, of course, terribly important to analyze case histories to discover potential triggers, mechanisms of transmission, and viable ways to contain the damage of financial contagion. The problem is, as these articles amply demonstrate, that there’s always a new virus or a mutation of a former one lurking in some corner of the financial world. We don’t know what it is or where it is. And, even if we had some inkling, there’s almost never enough time to develop a financial flu shot. –SeekingAlpha.com The latest insights on financial contagion and how both nations and investors can effectively deal with it. The domino-style structure in which the financial system exists is a perilous one. Although historically, the financial system has been able to deal with major shocks, the fact remains that our financial system is not as secure as it should be. Recent years have brought about too many examples of contagion and systemic risk. That is why Financial Contagion is such an important read. In it, the serious concerns that revolve around our fragile economic system are investigated, researched, and explained. Throughout the book, Kolb offers valuable insights on this dilemma as he compiles the history of financial contagion, highlights the latest research on systemic failure and interrelated markets, and analyzes the risks and consequences we face moving forward. Examines the importance of careful regulation and what must be done to stabilize the global financial system Includes contributed chapters from both academics and experienced professionals, offering a variety of perspectives and a rich interplay of ideas Details how close we are to witnessing a financial contagion that could devastate the world economy We have been harshly reminded of how fragile our economic ecosystem is. With Financial Contagion, you'll hold a better understanding of what needs to be done to strengthen our system and safeguard our financial future.

Brave New World Economy. Global Finance Threatens Our Future Brave New World Economy. Global Finance Threatens Our Future

Автор: Wilhelm Hankel

Год издания: 

An engaging look at the road to a sustained economic recovery The global finance system can be regulated to prevent massive credit fraud, tame capitalism, confront the sovereign debt crisis, and move towards investing in the real economy and full employment. «Obamanomics», and American reinvention can lead to a sustained economic recovery but only together with major domestic, European, and global monetary reforms in cooperation with emerging nations. For decades, the U.S. dollar has served as the world's reserve currency. But after the global market meltdown and the resulting massive stimulus spending meant to keep the Great Recession from becoming an even Greater Depression, confidence in America's ability to make good on its growing debt is at all-time lows. In Brave New World Economy: Global Finance Threatens Our Future, Wilhelm Hankel and Robert Isaak—two extremely controversial, yet highly respected experts on international economics and management—describe how «Obamanomics,» the Euro crisis, and shift of economic growth from the West to emerging economies, if handled properly, can lead to true economic stability and job creation. Highlights America's 'Great Bluff' bail-out strategy to cope with the crisis and the reforms Obamanomics must make to bring about sustainable job recovery Describes the risks and rewards of borrowing from future generations—in the United States, Europe, and the developing world—to save the current generation Details how money became separated from government control and why the interbanking credit system threatens western nations with bankruptcy, undermining pensions, and the human right to work Points out why nation-states need to go back to helping themselves and not rely on the false promises of regional integration and globalization Shows how legalizing underground labor will create more jobs How we arrived at this economic crossroads isn't as important as the decision as to which path to take. The Brave New World Economy points us in the right direction.

Аtlas of Rare and Threatened Bryophytes of Eastern Europe as Candidates to New European Red List / Атлас редких и исчезающих мохообразных Восточной Европы как кандидатов в новый Европейский краснокниж Аtlas of Rare and Threatened Bryophytes of Eastern Europe as Candidates to New European Red List / Атлас редких и исчезающих мохообразных Восточной Европы как кандидатов в новый Европейский краснокниж

Автор: Олег Масловский

Год издания: 

This book includes maps and descriptions of distribution and ecology of 376 species (336 maps) of most rare and threatened bryophytes on the territory of Eastern Europe. Mapping was made on 400 squares around 100 ? 100 km on base geographical map system – Universal Transverse Mercator (UTM) with help of original computer programs. Distribution of еhe species on the territory of 6 biogeography regions and 12 subregions are showed. This atlas may be useful for preparing of new edition of European Red Book of Bryophytes, another bryological investigations and nature protection activity.