Найти книгу: "Decoding the Genomic Control of Immune Reactions"

This book explores existing and potential strategies for using the genome sequences of human, mouse, other vertebrates and human pathogens to solve key problems in the treatment of immunological diseases and chronic infections. The assembled genome sequences now provide important opportunities for solving these problems, but a major bottleneck is the identification of key sequences and circuits controlling the relevant immune reactions. This will require innovative, interdisciplinary and collaborative strategies of a scale and complexity we are only now beginning to comprehend. Specific problems addressed include the following: What kinds of information are we lacking to understand how the genome sequence specifies the differentiation and response of immune system cells, and system behaviour such as immunological memory and tolerance? Which genome sequences and cellular circuits cause or prevent pathological immune responses to foreign pathogens, allergens or self-tissues? Which host and pathogen genome sequences and cellular circuits explain the failure of sterilizing immune responses to sophisticated human pathogens such as the agents of tuberculosis, malaria, metazoan parasites and chronic viruses? Containing contributions from a range of leading experts in the field, this book provides an important new perspective for clinical immunologists and basic researchers alike.

Все продавцы мечтают работать с ключевыми клиентами и заключать крупные сделки. Но, к сожалению, не многим это удается… и тому есть причины! Чтобы успешно сотрудничать с руководителями, принимающими ключевые решения, и VIP-партнерами, необходимо овладеть подходами и навыками, которые не используются в работе с другими клиентами. Иначе Вы просто не пройдете «фейс-контроль»! Почему? Потому что влиятельные люди мыслят, действуют и работают по другим правилам. Аудиокнига «Face Control. Правила назначения встреч, ведения переговоров и заключения сделок с VIP-клиентами» поможет продавцам овладеть навыками успешной работы с ключевыми клиентами и VIP-партнерами.

В книге описаны пакеты расширения Control System Toolbox и Robust Control Toolbox системы MATLAB 7, предназначенные для анализа и синтеза систем управления. Коротко изложены основные теоретические положения, принятые при разработке указанных пакетов расширения. Приведены многочисленные примеры использования этих пакетов расширения для решения конкретных задач с подробным пояснением выполняемых операций. Показаны возможности совместного использования пакетов Control System Toolbox и Robust Control Toolbox с пакетом Simulink, что увеличивает возможности всех трех указанных пакетов расширения. Книга может быть использована студентами вузов соответствующих специальностей при курсовом и дипломном проектировании, инженерами и научными работниками при создании новых и исследованиях уже разработанных систем автоматического управления. Книга рассчитана как на начинающих, так и на достаточно опытных пользователей.

The economic climate is ripe for another golden age of shareholder activism Deep Value: Why Activist Investors and Other Contrarians Battle for Control of Losing Corporations is a must-read exploration of deep value investment strategy, describing the evolution of the theories of valuation and shareholder activism from Graham to Icahn and beyond. The book combines engaging anecdotes with industry research to illustrate the principles and methods of this complex strategy, and explains the reasoning behind seemingly incomprehensible activist maneuvers. Written by an active value investor, Deep Value provides an insider's perspective on shareholder activist strategies in a format accessible to both professional investors and laypeople. The Deep Value investment philosophy as described by Graham initially identified targets by their discount to liquidation value. This approach was extremely effective, but those opportunities are few and far between in the modern market, forcing activists to adapt. Current activists assess value from a much broader palate, and exploit a much wider range of tools to achieve their goals. Deep Value enumerates and expands upon the resources and strategies available to value investors today, and describes how the economic climate is allowing value investing to re-emerge. Topics include: Target identification, and determining the most advantageous ends Strategies and tactics of effective activism Unseating management and fomenting change Eyeing conditions for the next M&A boom Activist hedge funds have been quiet since the early 2000s, but economic conditions, shareholder sentiment, and available opportunities are creating a fertile environment for another golden age of activism. Deep Value: Why Activist Investors and Other Contrarians Battle for Control of Losing Corporations provides the in-depth information investors need to get up to speed before getting left behind.