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The tools for detecting false positives, false negatives, and interference in interactions when testing and monitoring therapeutic drug use For physicians monitoring a patient's progress, efficacy of treatment is often linked to a patient's response to medication. Determining whether a patient is taking the prescribed amount, the drug or dosage is effective, or the prescribed medication is interacting with other drugs can be determined through drug testing. Written as a guide for toxicologists, chemists, and health professionals involved in patient care, Resolving Erroneous Reports in Toxicology and Therapeutic Drug Monitoring provides an up-to-date introduction to the tests and methodologies used in a toxicology lab as well as the sources of testing error that can lead to false positives, false negatives, and unreliable conclusions of drug abuse or under use. Covering a host of common therapeutic drugs as well as specific types of interference in immunoassays used in drug testing, the book details a number of possible testing scenarios and problems as well as solutions: False positive results in immunoassays for drugs in abuse testing Interferences in immunoassays used for monitoring anticonvulsants, tricyclic antidepressants, and digoxin False positive alcohol tests using breath analyzers and automated analyzers When a toxicology report is negative in a suspected overdose patient: the world of designer drugs Effects of drug-herb interactions on therapeutic drug monitoring Pharmacogenomics and the general principles of genetic analysis Approaches for eliminating interference/discordant specimen in therapeutic drug monitoring and drugs in abuse testing What to do in case there is no readily available method for testing Complete with easy-to-read tables and flowcharts, this book helps toxicologists, clinical chemists, clinical pathologists, and forensic pathologists develop accurate, unbiased drug monitoring and toxicology reports. Health care professionals involved in patient care, especially of critically ill patients, will find this guide indispensable in making sure lab tests are reliable enough to provide high-quality care. An indispensable handbook to the entire suite of toxicology lab tests, as well as all the possible sources of testing error, Resolving Erroneous Reports in Toxicology and Therapeutic Drug Monitoring offers clear remedies for eliminating and preventing testing error.

Much of the world’s petroleum is located on continental margins, and any further development of these offshore deposits would be impossible without new technologies and new methods contained in this volume. Written by some of the world’s foremost authorities on oil and gas, this volume explains for the practicing engineer and the engineering student some of the most important and cutting-edge techniques for developing offshore fields on continental margins.

The elucidation of the mechanisms and kinematics of shear zone deformation, at both local and regional scales, is the subject of a great deal of interest to scientists in the hydrocarbon industry, in seismology, and in structural geology more generally. This book comprises a collection of five theoretical and twelve regional contributions to the subject from a number of leading researchers in the field, with particular emphasis on work carried out in the Indian subcontinent. The book will be invaluable to advances students and researchers involved in the kinematics of shear.

Money is drawn to money. Many people think that this is just a beautiful metaphor, but far from everyone knows how much this expression is close to reality! If you want to know how money attracts to each other, forming cash flows, to which people they flock and why rich people get richer and the poor get poor – this book is for you!Find out from this book where your money is really hiding and why they are avoiding you! Raise your financial IQ by 8 points!

Transform your leadership with powerful lessons from the frontline Leading on the Frontline brings humanitarian leadership into the boardroom, giving business leaders a powerful lesson in engagement, motivation, inspiration and innovation. Drawing upon a lifetime of humanitarian work in some of the world’s most difficult places, author Linda Cruse shares stories from the frontline that illustrate how to dig deep, inspire, thrive and more. Business leaders work on a different type of frontline – one that is no less volatile, uncertain, complex and ambiguous – and the ability to deal effectively with the unexpected sets great leaders apart from the herd. Tap into your own intuition, compassion and courage; keep composure under pressure; align vision with strategic goals; exercise mental toughness – these skills are required in the aftermath of a tsunami in Thailand or a landslide in Nepal, and in business, they propel good people to great feats of leadership. This book presents extraordinary stories of extraordinary people who confront the best and worst of humanity every day. These people accomplish big things with few resources, prioritise progress over personal comfort and prevail over seemingly impossible odds. Their lessons contain multitudes for those who aspire to be great leaders – and the very best version of themselves. Learn the secrets of effective leadership through the frontline humanitarian lens Master the art of storytelling to build morale, strengthen teamwork and define problem solving paradigms See everyday situations in a new way, discover new possibilities and unearth new solutions Learn how extraordinary people confront fear, face death and find joy in the most difficult circumstances Whether on the frontline or in the boardroom, the objective is the same: to achieve goals and exceed expectations. Leading on the Frontline equips leaders with the skills and perspective they need to emerge victorious in a relentlessly volatile, constantly changing world.