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Hard strength and resilience are needed to survive each new day in the treacherous world of post nuclear America.For Ryan Cawdor and his companions, honour, integrity and a willingness to kill are necessary as well, as they struggle to balance a survivalist spirit with a warrior's resolve to press on, living by their own rules in a tortured land, pursuing a dream that leads them into the unknown….Ryan and his group make their way to a remote island in hopes of finding brief sanctuary. Instead, they are captured by an isolated tribe of descendants of African slaves from pre-Civil War days. When the tribesmen declare Mildred Wyeth «free» from her white masters, it is a twist of fate that ultimately leads the battle hardened medic to question where her true loyalties lie. Will she side with Ryan, J. B. Dix and those with whom she has forged a bond of trust and friendship…or with the people of her own blood? But the loss of Mildred is not the only threat the group faces–in a treacherous world where the ties that bind can cut both ways. In the Deathlands, the future is not what it used to be….

Introducing Proteomics gives a concise and coherent overview of every aspect of current proteomics technology, which is a rapidly developing field that is having a major impact within the life and medical sciences. This student-friendly book, based on a successful course developed by the author, provides its readers with sufficient theoretical background to be able to plan, prepare, and analyze a proteomics study. The text covers the following: Separation Technologies Analysis of Peptides/Proteins by Mass Spectrometry Strategies in Proteomics This contemporary text also includes numerous examples and explanations for why particular strategies are better than others for certain applications. In addition, Introducing Proteomics includes extensive references and a list of relevant proteomics information sources; essential for any student. This no-nonsense approach to the subject tells students exactly what they need to know, leaving out unnecessary information. The student companion site enhances learning and provides answers to the end of chapter problems. «I think this book will be a popular and valuable resource for students and newcomers to the field who would like to have an overview and initial understanding of what proteomics is about. The contents are well organized and address the major issues.» —Professor Walter Kolch, Director, Systems Biology Ireland & Conway Institute, University College Dublin Companion Website www.wiley.com/go/lovric

Discusses chiral separations and offers guidance for selecting the optimum method for desired results Chiral separations represent the most intriguing and, by some measures, most difficultseparations of chemical compounds. This book provides researchers and students an under-standing of chiral separations and offers a convenient route to selecting the best separation method, saving considerable time and cost in product development. Considering chiral separations in the biotechnological and pharmaceutical industries, as well as for food applications, Dr. Ahuja provides insights into a broad range of topics. Opening with a broad overview of chiral separations, regulatory considerations in drug product development, and basic issues in method development, the book: Covers a variety of modern methods such as gas chromatography, high performance liquid chromatography, supercritical fluid chromatography, and capillary electrophoresis Deals with the impact of chirality on the biological activity of small and large molecules Provides detailed information on useful chiral stationary phases (CSPs) for HPLC Includes handy information on selection of an appropriate CSP, including mechanistic studies Offers strategies for fast method development with HPLC, SFC, and CE Discusses preparatory methods utilized in the pharmaceutical industry With in-depth discussions of the current state of the field as well as suggestions to assist future developments, Chiral Separation Methods for Pharmaceutical and Biotechnological Products is an essential text for laboratory investigators, managers, and regulators who are involved in chiral separations in the pharmaceutical industry, as well as students preparing for careers in these fields.

A systematic exploration of both classic and contemporary algorithms in blind source separation with practical case studies The book presents an overview of Blind Source Separation, a relatively new signal processing method. Due to the multidisciplinary nature of the subject, the book has been written so as to appeal to an audience from very different backgrounds. Basic mathematical skills (e.g. on matrix algebra and foundations of probability theory) are essential in order to understand the algorithms, although the book is written in an introductory, accessible style. This book offers a general overview of the basics of Blind Source Separation, important solutions and algorithms, and in-depth coverage of applications in image feature extraction, remote sensing image fusion, mixed-pixel decomposition of SAR images, image object recognition fMRI medical image processing, geochemical and geophysical data mining, mineral resources prediction and geoanomalies information recognition. Firstly, the background and theory basics of blind source separation are introduced, which provides the foundation for the following work. Matrix operation, foundations of probability theory and information theory basics are included here. There follows the fundamental mathematical model and fairly new but relatively established blind source separation algorithms, such as Independent Component Analysis (ICA) and its improved algorithms (Fast ICA, Maximum Likelihood ICA, Overcomplete ICA, Kernel ICA, Flexible ICA, Non-negative ICA, Constrained ICA, Optimised ICA). The last part of the book considers the very recent algorithms in BSS e.g. Sparse Component Analysis (SCA) and Non-negative Matrix Factorization (NMF). Meanwhile, in-depth cases are presented for each algorithm in order to help the reader understand the algorithm and its application field. A systematic exploration of both classic and contemporary algorithms in blind source separation with practical case studies Presents new improved algorithms aimed at different applications, such as image feature extraction, remote sensing image fusion, mixed-pixel decomposition of SAR images, image object recognition, and MRI medical image processing With applications in geochemical and geophysical data mining, mineral resources prediction and geoanomalies information recognition Written by an expert team with accredited innovations in blind source separation and its applications in natural science Accompanying website includes a software system providing codes for most of the algorithms mentioned in the book, enhancing the learning experience Essential reading for postgraduate students and researchers engaged in the area of signal processing, data mining, image processing and recognition, information, geosciences, life sciences.

Separation and purification processes play a critical role in biorefineries and their optimal selection, design and operation to maximise product yields and improve overall process efficiency. Separations and purifications are necessary for upstream processes as well as in maximising and improving product recovery in downstream processes. These processes account for a significant fraction of the total capital and operating costs and also are highly energy intensive. Consequently, a better understanding of separation and purification processes, current and possible alternative and novel advanced methods is essential for achieving the overall techno-economic feasibility and commercial success of sustainable biorefineries. This book presents a comprehensive overview focused specifically on the present state, future challenges and opportunities for separation and purification methods and technologies in biorefineries. Topics covered include: Equilibrium Separations: Distillation, liquid-liquid extraction and supercritical fluid extraction. Affinity-Based Separations: Adsorption, ion exchange, and simulated moving bed technologies. Membrane Based Separations: Microfiltration, ultrafiltration and diafiltration, nanofiltration, membrane pervaporation, and membrane distillation. Solid-liquid Separations: Conventional filtration and solid-liquid extraction. Hybrid/Integrated Reaction-Separation Systems: Membrane bioreactors, extractive fermentation, reactive distillation and reactive absorption. For each of these processes, the fundamental principles and design aspects are presented, followed by a detailed discussion and specific examples of applications in biorefineries. Each chapter also considers the market needs, industrial challenges, future opportunities, and economic importance of the separation and purification methods. The book concludes with a series of detailed case studies including cellulosic bioethanol production, extraction of algae oil from microalgae, and production of biopolymers. Separation and Purification Technologies in Biorefineries is an essential resource for scientists and engineers, as well as researchers and academics working in the broader conventional and emerging bio-based products industry, including biomaterials, biochemicals, biofuels and bioenergy.

In one handy volume this handbook summarizes the most common synthetic methods for the separation of racemic mixtures, allowing an easy comparison of the different strategies described in the literature. Alongside classical methods, the authors also consider kinetic resolutions, dynamic kinetic resolutions, divergent reactions of a racemic mixture, and a number of «neglected» cases not covered elsewhere, such as the use of circularly polarized light, polymerizations, «ripening» processes, dynamic combinatorial chemistry, and several thermodynamic processes. The result is a thorough introduction to the field plus a long-needed, up-to-date overview of the chemical, biological, and physical methods and their applications. Newcomers to the field, students as well as experienced synthetic chemists will benefit from the highly didactic presentation: Every method is presented in detail, from relatively simple separation problems to advanced complex resolution methods.