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Enables researchers to assess the effects of endocrine disrupters as well as comply with new environmental regulations Endocrine disrupters are chemicals—both man-made and natural—that interfere with the body's endocrine system, potentially resulting in adverse developmental, reproductive, neurological, and immune effects. In recent years, a number of regulatory authorities around the world have drafted or enacted legislation that requires the detection and assessment of the effects of endocrine disrupters on both humans and wildlife. In response, this book provides comprehensive, up-to-date information on the latest tested and proven methods used to detect and assess the environmental hazards posed by endocrine-disrupting chemicals. Endocrine Disrupters is divided into chapters covering each major taxon as well as chapters dedicated to hazard assessment and regulation. The book covers testing methods for all the vertebrate groups and several invertebrate phyla, including: Crustaceans and mollusks Insects Fish Amphibians and reptiles Birds and mammals Moreover, the book emphasizes practical, ethical testing methods that combine sensitivity, efficiency, statistical power, and reasonable cost. Each chapter is written by one or more international experts in ecotoxicology, offering readers step-by-step guidance for implementing each method based on the latest research and the authors' firsthand laboratory experience. Furthermore, all the chapters have been subjected to a rigorous peer review and edited in light of the reviewers' comments. References at the end of each chapter guide readers to the literature in the field. Endocrine Disrupters is recommended for scientists who need to test chemicals for possible endocrine-disrupting properties. It is also recommended for regulatory authorities who need to decide whether particular chemicals can be safely marketed.

A concise and engaging overview of endocrine disruption phenomena that brings complex concepts within the reach of non-specialists For most of the last decade, the science of endocrine disruption has evolved with more definitive evidence of its damaging potential to health and environment. This book lists the major environmental chemicals of concern and their mechanism of endocrine disruption including remedial measures for them. Divided into three parts, Endocrine Disruptors in the Environment begins with an overview of the endocrine system and endocrine disruptors, discussing their salient features and presenting a historical perspective of endocrine disruption phenomena. It then goes on to cover hormone-signaling mechanisms, followed by various broad classes of putative endocrine disruptors, before introducing readers to environmental epigenetic modifications. Part two of the book focuses on removal processes of various EDCs by biotic and abiotic transformation/degradation. The last section consists of four chapters embracing themes on finding solutions to environmental EDCs—including their detection, regulation, replacement, and remediation. Endocrine Disruptors in the Environment is the first book to detail the endocrine effects of several known environmental contaminants and their mechanism of endocrine disruption. Additionally, it: Covers both the chemistry and biology of endocrine disruption and compiles almost all the known endocrine disrupting environmental chemicals and their mechanisms of toxicity Addresses policy and regulatory issues relevant to EDCs including scientific uncertainty and precautionary policy Brings forth the use of Green Chemistry principles in avoiding endocrine disruption in the designing and screening for safer chemicals and remediation of the EDCs in aquatic environment Includes a useful glossary of technical terms, a list of acronyms, topical references, and a subject index Endocrine Disruptors in the Environment is an ideal book for environmental chemists and endocrine toxicologists, developmental biologists, endocrinologists, epidemiologists, environmental health scientists and advocates, and regulatory officials tasked with risk assessment in environment and health areas.

The Endocrine System at a Glance provides a highly illustrated and unambiguous introduction to the basic principles and mechanisms of endocrinology and the key endocrine organs, followed by sections on reproductive and metabolic endocrinology. Clinical scenarios contextualise the basic science and illustrate how endocrine conditions present, are diagnosed, and are treated on the wards. This third edition: Includes new material on basic diagnostic tests used in the diagnosis of endocrine disorders Features new material on cancer and endocrinology Includes MCQs for each chapter The Endocrine System at a Glance is ideal for all medical students studying endocrinology and revising for final exams, as well as preparing for clinical attachments. The book is also suitable for those training in allied health professions and nurses specialising in endocrinology.

This valuable new addition to the Encyclopaedia of Sports Medicine series provides a comprehensive and logical look at the principles and mechanisms of endocrinology as related to sports and exercise. It looks at growth hormone factors involved in exercise and the endocrinology of sport competition. It considers various factors and stresses on the body that may alter sporting performance. It covers topics from the acute responses and chronic adaptations of the human endocrine system to the muscular activity involved in conditioning exercise, physical labor, and sport activities. This book is an essential reference for helping to plan better programs of physical fitness, to prepare for sports competitions, and to manage the medical care of athletes.

A truly comprehensive reference for the management of patients with endocrine cancer The new edition of Clinical Endocrine Oncology has been fully revised and extended making it the most comprehensive and up-to-date reference available. Written and edited by leading international experts in the field, it sets the standard in multidisciplinary care for patients with endocrine tumors. The book provides specific and detailed guidance on the basic, clinical, investigative and therapeutic processes required for the thorough evaluation of a patient with a tumor in an endocrine organ. The eighty-four chapters are arranged in seven parts: • Endocrine Oncology and Therapeutic Options • Thyroid and Parathyroid Tumors • Pituitary and Hypothalamic Lesions • Adrenal and Gonadal Tumors • Neuroendocrine Tumors and the Clinical Syndromes • Medical Syndromes and Endocrine Neoplasia • Endocrine-responsive Tumors and Female Reproductive Hormone Therapy. This authoritative and practical text will be an invaluable resource for all those working in the field, including endocrinologists, medical oncologists, surgeons, radiation therapists, interventional radiologists, specialist nurses, and clinical scientists. John A.H. Wass is joined in this edition by a new editor, Ian D. Hay, Professor of Medicine and Endocrinology Research at the Mayo Clinic College of Medicine, Rochester, Minnesota, USA.

The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.