Найти книгу: "Leachables and Extractables Handbook"

A practical and science-based approach for addressing toxicological concerns related to leachables and extractables associated with inhalation drug products Packaging and device components of Orally Inhaled and Nasal Drug Products (OINDP)—such as metered dose inhalers, dry powder inhalers, and nasal sprays—pose potential safety risks from leachables and extractables, chemicals that can be released or migrate from these components into the drug product. Addressing the concepts, background, historical use, and development of safety thresholds and their utility for qualifying leachables and extractables in OINDP, the Leachables and Extractables Handbook takes a practical approach to familiarize readers with the recent recommendations for safety and risk assessment established through a joint effort of scientists from the FDA, academia, and industry. Coverage includes best practices for the chemical evaluation and management of leachables and extractables throughout the pharmaceutical product life cycle, as well as: Guidance for pharmaceutical professionals to qualify and risk-assess container closure system leachables and extractables in drug products Principles for defining toxicological safety thresholds that are applicable to OINDP and potentially applicable to other drug products Regulatory perspectives, along with an appendix of key terms and definitions, case studies, and sample protocols Analytical chemists, packaging and device engineers, formulation development scientists, component suppliers, regulatory affairs specialists, and toxicologists will all benefit from the wealth of information offered in this important text.

Other enhancements and options that have been added and that you can find in this book are related to subjects such as the following: Availability is increased, and there are now further options for distributing the system, along with new powerful platforms. ? There is a new change and transport system, including all the facilities of the Transport Management System (TMS). ? In the ABAP workbench, there are a host of new utilities, a stepforward object?oriented ABAP, the replacement of matchcodes with search helps, and more. ? Windows NT is now a very popular platform with thousands of customers. For this reason, this new edition is operating system independent, dealing with both UNIX and Windows NT where appropriate. ? ? The authorization system and administrator duties have been facilitated with the profile generator. ? Since release 4.0 there is a new object?based monitoring architecture and alert monitors. ? The well?known OSS has now become SAPnet, with two variants: R/3 front end and Web front end. In this edition you will find lots of new things to discover and enjoy. I hope you enjoy this book and enjoySAP.

Oxford Handbook of Commercial Correspondence - это справочник по всем аспектам деловой переписки на английском языке. Справочник неоднократно переиздавался. Существует также сборник упражнений по деловому письму, который можно приобрести отдельно. Его название - Oxford Correspondence Workbook.

Тематика данной памятки – ветераны боевых действий. Правовая основа. Льготы. Пособия. Выплаты. Социальный статус. Памятка Beketoff handbook – краткая подборка информации по определённой тематике с перечнем юридических (правовых) документов, рекомендациями и практическими обзорами. Для чего я писал эту памятку? Являясь ветераном боевых действий, я решил структурировать и обобщить информацию, которая касается данной тематики. Думаю, результаты моего труда могут быть полезны ещё кому-то.

Книга написана больничным клоуном и подойдет детям, проходящим лечение в больнице, их родителям, врачам и медицинским сестрам, будущим и настоящим клоунам, а также актерам и всем тем, кто хочет узнать об уникальной и важной профессии – больничный клоун. Вместе с Фросей вы попробуете отыскать своего внутреннего клоуна и увидеть мир сквозь красный нос. Удачи!