Найти книгу: "Drug Delivery Applications of Noninvasive Imaging. Validation from Biodistribution to Sites of Action"

Cost-effective strategies for designing novel drug delivery systems that target a broad range of disease conditions In vivo imaging has become an important tool for the development of new drug delivery systems, shedding new light on the pharmacokinetics, biodistribution, bioavailability, local concentration, and clearance of drug substances for the treatment of human disease, most notably cancer. Written by a team of international experts, this book examines the use of quantitative imaging techniques in designing and evaluating novel drug delivery systems and applications. Drug Delivery Applications of Noninvasive Imaging offers a full arsenal of tested and proven methods, practices and guidance, enabling readers to overcome the many challenges in creating successful new drug delivery systems. The book begins with an introduction to molecular imaging. Next, it covers: In vivo imaging techniques and quantitative analysis Imaging drugs and drug carriers at the site of action, including low-molecular weight radiopharmaceuticals, peptides and proteins, siRNA, cells, and nanoparticles Applications of imaging techniques in administration routes other than intravenous injection, such as pulmonary and oral delivery Translational research leading to clinical applications Imaging drug delivery in large animal models Clinical applications of imaging techniques to guide drug development and drug delivery Chapters are based on a thorough review of the current literature as well as the authors' firsthand experience working with imaging techniques for the development of novel drug delivery systems. Presenting state-of-the-technology applications of imaging in preclinical and clinical evaluation of drug delivery systems, Drug Delivery Applications of Noninvasive Imaging offers cost-effective strategies to pharmaceutical researchers and students for developing drug delivery systems that accurately target a broad range of disease conditions.

The personal home page (PHP) server-side scripting language is particular well adapted to connecting HTML-based web pages to a backend database for dynamic content. This book explains the entire nuts-and-bolts process of the PHP application life cycle: requirements, design, development, maintenance and tuning. It shows how PHP can be used to design and develop highly manageable and secure applications to solve practical problems.

Written by members of the Oracle XML group, this is a must-have reference for all IT managers, DBAs, and developers who want to learn the best practices for using XML with Oracle’s XML-enabled products. Includes real-world case studies based on theauthors’ experience managing Oracle’s XML Discussion Forum - a community of 20,000+ XML component users.

Rizzoni is designed for the sophomore/junior level, Introduction to Electrical Engineering course required for non-EE majors. The most widely used book for this course, Rizzoni introduces non-majors to the three basic areas of electrical engineering: circuits, electronics, and electromechanics. The second edition continues the tradition of focusing on the topics and issues of interest to the non-electrical engineering student. To maintain student interest in these topics, Rizzoni provides numerous links between electrical engineering and other engineering fields.

Эта книга будет полезной как пользователям Internet, желающим овладеть непростым искусством разработки интерактивных Web-узлов, так и опытным сетевым администраторам, поддерживающим корпоративные сети и Web-серверы. Подробно рассмотрен язык программирования ActionScript, включая отладку готовых сценариев. Здесь вы найдете множество практических примеров, иллюстрирующих теоретические концепции, а весь рассматриваемый в книге программный код находится на прилагаемом к книге компакт-диске.

The creator of Tapestry details how to use this new framework's components to create rich web-based GUIs using links, images, and HTML forms. The challenges of web application development are discussed, such as managing server-side state properly, application localization, and maintaining synchronization between the client web browser and the application server. At the same time, the benefits of a clean separation between presentation logic and business logic and how well Tapestry succeeds in keeping these two concerns apart are identified. Targeted to new Tapestry users and even developers new to creating web applications in general, this guide includes extensive notes on development "gotchas", including common Tapestry errors and how to fix them. Advanced techniques are covered as well, including creating entirely new components, integration with traditional servlet and JSP applications, and creation of client-side javascript. Finally, a complete J2EE application, the Virtual Library, is presented and analyzed in detail.