Скачать книгу - Captured by Moonlight

Gold Medal Winner, Success and Motivation, 2011 Axiom Business Book Awards Insight from leaders who experienced major setbacks and redefined success In tough economic times, when careers are derailed and leaders are forced to rewrite their professional plans, this book enlightens and uplifts. Comebacks features an all-star cast of ten leaders who endured setbacks-for some a public fall in the midst of media scrutiny-then reassessed and moved ahead with new purpose. Based on revealing interviews, the book presents a behind-the–headlines glimpse into the lives of leaders; how they drew upon resources, both internal and external, to move on; and the lessons that helped them redefine success. Leaders profiled include: Jacques Nasser, former CEO of Ford Motor Co., recently appointed Chairman of BHP Billiton, the world's largest natural resources company Patricia Dunn, former Chair of Hewlett-Packard, vilified for her alleged role in corporate espionage only to be exonerated from all charges, today active in philanthropy Jamie Dimon (JP Morgan), Herbert «Pug» Winokur (Enron Corp.), David Neeleman (JetBlue), and more Redmond, a top executive recruiter, and Crisafulli, author of The House of Dimon, show how all leaders face adversity, but true leaders turn adversity into success.

Moonlighting Proteins: Novel Virulence Factors in Bacterial Infections is a complete examination of the ways in which proteins with more than one unique biological action are able to serve as virulence factors in different bacteria. The book explores the pathogenicity of bacterial moonlighting proteins, demonstrating the plasticity of protein evolution as it relates to protein function and to bacterial communication. Highlighting the latest discoveries in the field, it details the approximately 70 known bacterial proteins with a moonlighting function related to a virulence phenomenon. Chapters describe the ways in which each moonlighting protein can function as such for a variety of bacterial pathogens and how individual bacteria can use more than one moonlighting protein as a virulence factor. The cutting-edge research contained here offers important insights into many topics, from bacterial colonization, virulence, and antibiotic resistance, to protein structure and the therapeutic potential of moonlighting proteins. Moonlighting Proteins: Novel Virulence Factors in Bacterial Infections will be of interest to researchers and graduate students in microbiology (specifically bacteriology), immunology, cell and molecular biology, biochemistry, pathology, and protein science. About the Editor Brian Henderson, Division of Infection and Immunity, University College London, London, UK

The past 25 years has seen the emergence of a wealth of data suggesting that novel biological functions of known proteins play important roles in biology and medicine. This ability of proteins to exhibit more than one unique biological activity is known as protein moonlighting. Moonlighting proteins can exhibit novel biological functions, thus extending the function of the proteome, and are also implicated in the pathology of a growing number of idiopathic and infectious diseases. This book, written by a cell biologist, protein evolutionary biologist and protein bioinformatician, brings together the latest information on the structure, evolution and biological function of the growing numbers of moonlighting proteins that have been identified, and their roles in human health and disease. This information is revealing the enormous importance protein moonlighting plays in the maintenance of human health and in the induction of disease pathology. Protein Moonlighting in Biology and Medicine will be of interest to a general readership in the biological and biomedical research community.