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During the last several decades, the study of nuclear shapes has been of prime importance. A large number of investigations, both theoretical and experimental, have led to the discovery of a rich variety of nuclear shapes like, the basic spherical, deformed, superdeformed, triaxial, shape coexistence, reflection asymmetric (pear-shape) and other exotic ones. Apart from common nuclear structural properties, each of the mentioned shapes manifests properties associated with its specific form. It is interesting to note that most deformed nuclei are prolate deformed. In this monograph, attention is paid to pear-shaped nuclei.Contents: <ul><li>The Pear-Shaped Nuclei</li><li>Ground-State Nuclear Shape Deformations</li><li>High Spin Behavior of Pear-Shaped Nuclei — I</li><li>High Spin Behavior of Pear-Shaped Nuclei — II</li><li>Status, Conclusions and Perspectives</li></ul> Readership: Advance nuclear physics students and young researchers in nuclear structure physics.Nuclear Structure Physics;Pear-shaped Nuclei0Key Features:<ul><li>A pedagogical approach for beginners in research or young researchers in nuclear structure physics</li><li>Provides the readers with an up-to-date subject knowledge in a consolidated and focused manner</li><li>Will be very useful for advanced nuclear physics class teaching in Universities and Institutions</li><li>Based on numerous painstaking investigations, both theoretical and experimental, over several decades by a large number of physicists</li> <li>Emphasis more on experimental findings</li></ul>

M&A Titans. The Pioneers Who Shaped Wall Street's Mergers and Acquisitions Industry

Автор: Brett Cole

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This book focuses on the 11 men, lawyers and bankers, who are responsible for the creation of Wall Street's merger industry. It specifically concentrates on the events and personalities who dominated Wall Street during the takeover battles of the 1970s and 1980s. Lawyers Joe Flom and Marty Lipton, the godfathers of modern M&A, educated bankers on takeover laws and regulations as well as tactics. Flom and Lipton were also superlative businessmen who built their own firms to become Wall Street powerhouses. The two men drew into their orbit a circle of bankers. Felix Rohatyn, Ira Harris, Steve Friedman, Geoff Boisi, Eric Gleacher and Bruce Wasserstein were close to Lipton. Robert Greenhill and Joe Perella were close to Flom. M&A Titans provides insight into the culture of the different investment banks and how each of the bankers influenced the firms they worked in as they became more powerful. Some such as Gleacher, Harris, Wasserstein, Perella and Greenhill clashed with the men running their firms and left. Others such as Friedman and Boisi stayed and profoundly influenced how the firm did business. The career of Michael Milken, perhaps the notorious name on Wall Street in the 1980s, is also examined as well as the actions and tactics of his firm, Drexel Burnham Lambert. Milken and Drexel paved the way for the growth of private equity and helped popularize attacks on management by investors such as Boone Pickens and Carl Icahn.

Understanding Medical Research. The Studies That Shaped Medicine

Автор: John Goodfellow A.

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Medical students and junior and senior doctors are frequently called upon to give research presentations, write reports, and answer exam questions on specific areas of medical research. Understanding Medical Research: The Studies That Shaped Medicine is an exciting new title that offers a unique and valuable approach to understanding historically influential studies in important areas of medicine. Featuring chapters from Sir Liam Donaldson and Sir David Weatherall, amongst others, world leading researchers identify ten primary research papers that have shaped the direction of research in their given topic, examining why they were carried out, key findings, and how they changed the field. Each chapter also contains short sections on ‘Key Questions Remaining’ which outline outstanding areas where further research is needed, and a link to ‘Key Laboratories/Clinics’ which point the reader to major research groups of international standing. Covering the seminal research in core areas of medicine, Understanding Medical Research provides an authoritative framework on each topic for medical students and healthcare professionals.

The Chemical Biology of Nucleic Acids

Автор: Gunter Mayer

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With extensive coverage of synthesis techniques and applications, this text describes chemical biology techniques which have gained significant impetus during the last five years. It focuses on the methods for obtaining modified and native nucleic acids, and their biological applications. Topics covered include: chemical synthesis of modified RNA expansion of the genetic alphabet in nucleic acids by creating new base pairs chemical biology of DNA replication: probing DNA polymerase selectivity mechanisms with modified nucleotides nucleic-acid-templated chemistry chemical biology of peptide nucleic acids (PNA) the interactions of small molecules with DNA and RNA the architectural modules of folded RNAs genesis and biological applications of locked nucleic acid (LNA) small non-coding RNA in bacteria microRNA-guided gene silencing nucleic acids based therapies innate immune recognition of nucleic acid light-responsive nucleic acids for the spatiotemporal control of biological processes DNA methylation frameworks for programming RNA devices RNA as a catalyst: The Diels-Alderase-Ribozyme evolving an understanding of RNA function by in vitro approaches the chemical biology of aptamers: synthesis and applications nucleic acids as detection tools bacterial riboswitch discovery and analysis The Chemical Biology of Nucleic Acids is an essential compendium of the synthesis of nucleic acids and their biological applications for bioorganic chemists, chemical biologists, medicinal chemists, cell biologists, and molecular biologists.

Complex-shaped Metal Nanoparticles. Bottom-Up Syntheses and Applications

Автор: Sau Tapan K.

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The past few years have witnessed the development of non-spherical metal nanoparticles with complex morphologies, which offer tremendous potential in materials science, chemistry, physics and medicine. Covering all important aspects and techniques of preparation and characterization of metal nanoparticles with controlled morphology and architecture, this book provides a sound overview – from the basics right up to recent developments. Renowned research scientists from all over the world present the existing knowledge in the field, covering theory and modeling, synthesis and properties of these nanomaterials. By emphasizing the underlying concepts and principles in detail, this book enables researchers to fully recognize the future research scope and the application potential of the complex-shaped metal nanoparticles, inspiring further research in this field.

Nucleic Acids as Molecular Diagnostics

Автор: Keller Andreas

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By integrating technology, supporting infrastructure and efficient application, the all-in-one guide presents molecular diagnostics as an essential component of modern, personalized clinical practice. It considers all important aspects, from the hardware and software needed, to recent improvements in blood- and non-blood-based biomarker tests. Chapters on ethical challenges and a look at current trends and the latest innovations are also included. Bridging the gap between industry and academia, this is a highly useful resource for practitioners as well as for developers of modern, DNA- and RNA-based molecular diagnostics.