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How protein chaperones protect cells from neurodegenerative diseases Including contributions from leading experts, Protein Chaperones and Protection from Neurodegenerative Diseases provides an in-depth exploration of how protein chaperones are involved in shielding cells from toxic aggregated or misfolded protein states that cause ALS, Parkinson's, and related diseases. Examining how different protein chaperones ameliorate the toxicity of proteins that are known to cause neurodegenerative damage, the book addresses both research and clinical perspectives on chaperone and anti-chaperone properties. The intersection of molecular chaperones and neurodegeneration is an intensely studied area, partly because of the potential for manipulating the expression of molecular chaperones to thwart the progression of debilitating diseases, and partly because of the ever-aging global population. Discussing the potential to harness the power of protein chaperones, and future directions for research, discovery, and therapeutics, this book is essential reading for scientists working in the fields of biochemistry, molecular medicine, pharmacology and drug discovery, biotechnology and pharmaceutical companies, advanced students, and anyone interested in this cutting-edge topic.

Always The Chaperon And Never The Bride…At least, that's the way it was for Lady Annis Wyncherley. If this young widow was to remain as chaperon to society's misses, there could be no hint of scandal attached to her name. Rakes and romance were strictly off-limits, most especially a rogue like the handsome Lord Adam Ashwick!But that proved nearly impossible when Adam made his daughter's chaperon the subject of his relentless seduction. Adam knew any attention from him could destroy Lady Wyncherley's fine reputation. But he was powerless to control the strong desires she aroused in him. And all too soon this reformed rogue was hell-bent on convincing a very stubborn Annis to become his chaperon bride….

A lord…a widow…a chance worth taking!Lord Frant is haunted by his experiences in India, which left him scarred and with an enemy at his back! Love is the last thing on his mind! Until, that is, he meets his ward’s beautiful new chaperon, Lady Jane March…After the death of her husband, Jane resolved not to marry again. But when Paul's dangerous life catches up with him, she throws caution to the wind. Together, they must chase away the past and find a new future!

‘Ten Thousand Pounds to Whoever Can Seduce the Heiress by Michaelmas!’Even for dissolute rake Richard Arrandale, this latest bet is outrageously scandalous. But Richard doesn’t care – until he meets the heiress’s charming chaperon and the stakes are raised even higher!Widowed Lady Phyllida Tatham is no longer the shy, plain creature she once was, and she’s determined to protect her beautiful stepdaughter. But there’s one suitor – with the worst kind of reputation – who seems more interested in seducing her. Who will come out on top in this winner-takes-all game?The Infamous Arrandales: scandal is their destiny!