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This keenly awaited first overview of the field represents a complete guide to the structure and function of the most important mammalian cell membrane organelles. Filling a huge gap in the primary literature, this book is the first to cover the subject in detail. Following an introduction by Kai Simons, the discoverer of lipid rafts and the most prominent scientist in the field, chapters include: Historical background Distinct structures and functions Structural basis Signaling Viral entry and virion budding Cholesterol transport Caveolins Lipid shells Cell polarity and intracellular trafficking Cancer cells Of prime importance to molecular and cell biologists, biochemists, membrane scientists, cancer researchers, and virologists.


Arts and Crafts with Children Arts and Crafts with Children

Автор: Andrew Wright

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Art, craft, and design activities offer children an excellent way to learn language while developing creative skills and an awareness of the world around them.


How to Make Money Using Etsy. A Guide to the Online Marketplace for Crafts and Handmade Products How to Make Money Using Etsy. A Guide to the Online Marketplace for Crafts and Handmade Products

Автор: Timothy Adam

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In a world where most products are manufactured by machines, Etsy offers an online platform for makers of handmade products and crafts to market and sell their goods to a vast network of buyers who demand unique, genuine products. To date, the site has attracted over 400,000 sellers who collectively have sold over 30 million items, generating more than $180.6 million in revenue. The only resource of its kind, How to Make Money Using Etsy–written by Tim Adam who has successfully been selling his products all over the world through his Etsy shop since 2007–guides readers step-by-step through the many stages of selling online. How-to topics include: Establish your Etsy shop Effectively photograph your products Post your products to optimize visibility and increase sales Brand your business Use social media like blogs, Twitter, and Facebook to connect with buyers and grow your business


Lipids and Essential Oils as Antimicrobial Agents Lipids and Essential Oils as Antimicrobial Agents

Автор: Halldor Thormar

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Lipids and essential oils have strong antimicrobial properties – they kill or inhibit the growth of microbes such as bacteria, fungi, or viruses. They are being studied for use in the prevention and treatment of infections, as potential disinfectants, and for their preservative and antimicrobial properties when formulated as pharmaceuticals, in food products, and in cosmetics. Lipids and Essential Oils as Antimicrobial Agents is a comprehensive review of the scientific knowledge in this field. International experts provide summaries on: the chemical and biological properties of lipids and essential oils use of lipids and essential oils in pharmaceuticals, cosmetics and health foods antimicrobial effects of lipids in vivo and in vitro antimicrobial lipids in milk antimicrobial lipids of the skin antibacterial lipids as sanitizers and disinfectants antibacterial, antifungal, and antiviral activities of essential oils antimicrobial lipids in milk antimicrobial lipids of the skin antibacterial lipids as sanitizers and disinfectants antibacterial, antifungal, and antiviral activities of essential oils Lipids and Essential Oils as Antimicrobial Agents is an essential guide to this important topic for researchers and advanced students in academia and research working in pharmaceutical, cosmetic and food sciences, biochemistry and natural products chemistry, microbiology; and for health care scientists and professionals working in the fields of public health and infectious diseases. It will also be of interest to anyone concerned about health issues and particularly to those who are conscious of the benefits of health food and natural products.


Lipids and Cellular Membranes in Amyloid Diseases Lipids and Cellular Membranes in Amyloid Diseases

Автор: Raz Jelinek

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Addressing one of the biggest riddles in current molecular cell biology, this ground-breaking monograph builds the case for the crucial involvement of lipids and membranes in the formation of amyloid deposits. Tying together recent knowledge from in vitro and in vivo studes, and built on a sound biophysical and biochemical foundation, this overview brings the reader up to date with current models of the interplay between membranes and amyloid formation. Required reading for any researcher interested in amyloid formation and amyloid toxicity, and possible avenues for the prevention or treatment of neurodegenerative disorders. From the contents: * Interactions of Alpha-Synuclein with Lipids * Interaction of hIAPP and its Precursors with Membranes * Amyloid Polymorphisms: Structural Basis and Significance in Biology and Molecular Medicine * The Role of Lipid Rafts in Alzheimer's Disease * Alzheimer's Disease as a Membrane-Associated Enzymopathy of Beta-Amyloid Precursor Protein (APP) Secretases * Impaired Regulation of Glutamate Receptor Channels and Signaling Molecules by Beta-Amyloid in Alzheimer's Disease * Membrane Changes in BSE and Scrapie * Experimental Approaches and Technical Challenges for Studying Amyloid-Membrane Interactions and more


Catalytic Asymmetric Friedel-Crafts Alkylations Catalytic Asymmetric Friedel-Crafts Alkylations

Автор: Bandini Marco

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This first comprehensive overview of this important synthetic reaction covers the whole spectrum of this modern and rapidly developing field. Clearly structured, the book presents all the known synthetic approaches for the construction of aromatic compounds bearing benzylic stereocenters with a defined configuration. With its representative synthetic procedures, organocatalysis and industrial applications it combines a theoretical basis with practical examples, resulting in valuable advice for beginners and experts alike. The ultimate source for every synthetic chemist in academia and industry.