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The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.


A Damaged Reputation A Damaged Reputation

Автор: Bindloss Harold

Год издания: 



A Quantitative Approach to Commercial Damages. Applying Statistics to the Measurement of Lost Profits A Quantitative Approach to Commercial Damages. Applying Statistics to the Measurement of Lost Profits

Автор: Mark Filler G.

Год издания: 

How-to guidance for measuring lost profits due to business interruption damages A Quantitative Approach to Commercial Damages explains the complicated process of measuring business interruption damages, whether they are losses are from natural or man-made disasters, or whether the performance of one company adversely affects the performance of another. Using a methodology built around case studies integrated with solution tools, this book is presented step by step from the analysis damages perspective to aid in preparing a damage claim. Over 250 screen shots are included and key cell formulas that show how to construct a formula and lay it out on the spreadsheet. Includes Excel spreadsheet applications and key cell formulas for those who wish to construct their own spreadsheets Offers a step-by-step approach to computing damages using case studies and over 250 screen shots Often in the course of business, a firm will be damaged by the actions of another individual or company, such as a fire that shuts down a restaurant for two months. Often, this results in the filing of a business interruption claim. Discover how to measure business losses with the proven guidance found in A Quantitative Approach to Commercial Damages.


Measuring Business Interruption Losses and Other Commercial Damages Measuring Business Interruption Losses and Other Commercial Damages

Автор: Patrick Gaughan A.

Год издания: 

An updated explanation of the methodology for how lost profits should be measured Now fully revised and updated, focused on commercial litigation and the many common types of cases, this is the only book in the field to explain the complicated process of measuring business interruption damages. The book features an easy to understand and apply, step-by-step process for how losses should be measured so as to be accurate and reliable and consistent with the relevant laws. With a new chapter on the economics of punitive damages, the new edition also explains detailed methods for measuring damages in contract litigation, intellectual property lawsuits, antitrust, and securities cases. This new Second Edition incorporates the latest developments in the fields of economics and accounting, while also integrating the most current changes in case law. Here's what you will find Each chapter includes new materials and updated content Added websites for sources of data Includes a website for updated tables that can be utilized by readers A section of the new cases involving Daubert challenges to economists Includes methods on how to do industry research A new section covering the equity risk premium and the various recent research studies, which set forth the debate on what the premium should be Containing exhibits, tables, and graphs, new cases involving Dauber, how to do industry research, equity risk premium, research studies on the marketability discount, anti-trust, punitive damages, and more, Measuring Business Interruption Losses and Other Commercial Damages, Second Edition incorporates the relevant literature and research that has come out in this field over the past four years.


Damage Mechanics in Metal Forming. Advanced Modeling and Numerical Simulation Damage Mechanics in Metal Forming. Advanced Modeling and Numerical Simulation

Автор: Khemais Saanouni

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The aim of this book is to summarize the current most effective methods for modeling, simulating, and optimizing metal forming processes, and to present the main features of new, innovative methods currently being developed which will no doubt be the industrial tools of tomorrow. It discusses damage (or defect) prediction in virtual metal forming, using advanced multiphysical and multiscale fully coupled constitutive equations. Theoretical formulation, numerical aspects as well as application to various sheet and bulk metal forming are presented in detail. Virtual metal forming is nowadays inescapable when looking to optimize numerically various metal forming processes in order to design advanced mechanical components. To do this, highly predictive constitutive equations accounting for the full coupling between various physical phenomena at various scales under large deformation including the ductile damage occurrence are required. In addition, fully 3D adaptive numerical methods related to time and space discretization are required in order to solve accurately the associated initial and boundary value problems. This book focuses on these two main and complementary aspects with application to a wide range of metal forming and machining processes. Contents 1. Elements of Continuum Mechanics and Thermodynamics. 2. Thermomechanically-Consistent Modeling of the Metals Behavior with Ductile Damage. 3. Numerical Methods for Solving Metal Forming Problems. 4. Application to Virtual Metal Forming.


Stable Radicals. Fundamentals and Applied Aspects of Odd-Electron Compounds Stable Radicals. Fundamentals and Applied Aspects of Odd-Electron Compounds

Автор: Robin Hicks

Год издания: 

Stable radicals – molecules with odd electrons which are sufficiently long lived to be studied or isolated using conventional techniques – have enjoyed a long history and are of current interest for a broad array of fundamental and applied reasons, for example to study and drive novel chemical reactions, in the development of rechargeable batteries or the study of free radical reactions in the body. In Stable Radicals: Fundamentals and Applied Aspects of Odd-Electron Compounds a team of international experts provide a broad-based overview of stable radicals, from the fundamental aspects of specific classes of stable neutral radicals to their wide range of applications including synthesis, materials science and chemical biology. Topics covered include: triphenylmethyl and related radicals polychlorinated triphenylmethyl radicals: towards multifunctional molecular materials phenalenyls, cyclopentadienyls, and other carbon-centered radicals the nitrogen oxides: persistent radicals and van der Waals complex dimers nitroxide radicals: properties, synthesis and applications the only stable organic sigma radicals: di-tert-alkyliminoxyls. delocalized radicals containing the hydrazyl [R2N-NR] unit metal-coordinated phenoxyl radicals stable radicals containing the thiazyl unit: synthesis, chemical, and materials properties stable radicals of the heavy p-block elements application of stable radicals as mediators in living-radical polymerization nitroxide-catalyzed alcohol oxidations in organic synthesis metal-nitroxide complexes: synthesis and magneto-structural correlations rechargeable batteries using robust but redox-active organic radicals spin labeling: a modern perspective functional in vivo EPR spectroscopy and imaging using nitroxides and trityl radicals biologically relevant chemistry of nitroxides Stable Free Radicals: Fundamentals and Applied Aspects of Odd-Electron Compounds is an essential guide to this fascinating area of chemistry for researchers and students working in organic and physical chemistry and materials science.