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2012 PROSE Award, Clinical Medicine: Honorable Mention The vast majority of medically important pathogens infect their host across a body surface such as the skin, or across a mucosal tissue such as the respiratory tract or intestines, as these sites are the ones exposed to the external environment. By focusing on immunity at mucosal and body surfaces this book presents a fresh, new approach to the teaching of immunology. After an introduction to the basic structure of the immune system, the book looks at two important families of signalling molecules: cytokines and chemokines, before covering the workings of the mucosal immune system. It continues by examining immunity against the four major groups of pathogens – viruses, bacteria, fungi and parasites, and concludes by looking at disorders of the immune system, mucosal tumour immunology and the process of vaccination. A fresh, new approach to the subject focusing on mucosal and body surfaces. Describes the mucosal immune systems of the gastrointestinal, respiratory and urogenital tracts, as well as the skin. Details the important roles of cytokines and chemokines in an immune response. Separate chapters devoted to immunity against viruses, bacteria, fungi and parasites. Includes chapter summaries, boxes with topics of special interest and an extensive glossary. Clearly written and well- illustrated in full colour throughout. Students across a range of disciplines, including biology, biochemistry, biomedicine, medicine and veterinary sciences, will find this book invaluable, both as an introduction to basic immunology and as a guide to mucosal immune defence mechanisms.

Want to learn how to use EUS in the treatment of pancreatic cysts? Need a refresher on how to perform EUS fine needle aspiration? This is the book for you! There have been dramatic changes since endoscopic ultrasound (EUS) was first introduced 30 years ago. Advances in technology have meant that as well as being used in the diagnosis of gastrointestinal disorders, EUS is now an accepted therapeutic modality. This second edition covers these exciting changes with new chapters on the emerging field of therapeutic EUS. The book provides a technical how-to approach to learning this advanced endoscopic procedure. The authors guide you, step-by-step, through the fundamentals of EUS with instructions on: the instruments involved sedation procedures how EUS should be performed Each chapter discusses a specific aspect of EUS as it relates to a particular gastrointestinal disorder or organ system. Drawing on the vast experience of the authors, this definitive volume contains clear and practical guidance on the state of the art in EUS practice today.

Offering the unique dual perspective of neurosurgeons and otolaryngologists, <em>Endoscopic Pituitary Surgery: Endocrine, Neuro-Ophthalmologic and Surgical Management</em> describes both cutting-edge endoscopic techniques and tried-and-true decision-making methodologies that lead to the most successful outcomes. From choosing the right surgical or non-surgical approach for individual patients, to managing complex endocrine and neuro-ophthalmologic issues, this is the first major reference in the field in nearly a decade, making it the go-to guide for all interdisciplinary specialists who treat pituitary tumors.<strong>Special Features:</strong><li>Step-by-step descriptions of the newest endoscopic pituitary and skull base procedures, ensuring that specialists have full mastery of techniques for different tumor types in this surgically challenging area</li><li>The clinical wisdom and perspectives of the masters of pituitary surgery, who share insights on patient selection, endoscopic versus open procedures, medical management, and much more</li><li>Operative pearls from both neurosurgeons and otolaryngologists</li><li>Compelling discussions of the pros and cons of various procedures (e.g., the utility of intraoperative MRI in pituitary surgery cases)</li><li>Inclusion of detail-revealing 3D endoscopic images (complete with 3D glasses)</li><li>Rationale for a collaborative neurosurgery–otolaryngology team approach to developing and implementing the most innovative endoscopic and skull base techniques</li>Enhanced by hundreds of images, decision-making algorithms, and clinical pearls from experts on each tumor type, <em>Endoscopic Pituitary Surgery</em> is a comprehensive guide representing the current palette of available treatment options. It is indispensable for residents in training as well as for practicing neurosurgeons and otolaryngologists who are making the transition to the newest minimally invasive endoscopic procedures in the treatment of pituitary lesions.