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The International Centre-Museum named after Nicholas Roerich (ICR) with a status of a public cultural enlightening centre was founded by the initiative of Svetoslav, the younger son of Helena and Nicholas Roerich. In 1990, Svetoslav Roerich transferred the invaluable heritage of his parents from India to Russia on the condition that a public Museum was to be established in Moscow. The management of the future Museum was entrusted to his good friend Lyudmila Shaposhnikova – a writer and specialist in Indian culture, who was appointed by Svetoslav as his trustee. Due to Shaposhnikova’s efforts and with support from the famous diplomat Yuli Vorontsov and sponsor Boris Bulochnik, Svetoslav’s will was fulfilled. The public Museum in Moscow became the second museum in the world founded by a member of the great family, the first one founded by Nicholas and Helena Roerich in New York.

The publication of the second edition of this manual comes at an important juncture in the history of clinical research. As advances in information technology make it possible to link individuals and groups in diverse locations in jointly seeking the answers to pressing global health problems, it is critically important to remain vigilant about moral and ethical safeguards for every patient enrolled in a trial. Those who study this manual will be well aware of how to ensure patient safety along with fiscal responsibility, trial efficiency, and research integrity. —Robert Harrington, Professor of Medicine, Director, Duke Clinical Research Institute, Durham, North Carolina, USA The Duke Clinical Research Institute (DCRI) is one of the world's leading academic clinical research organizations; its mission is to develop and share knowledge that improves the care of patients around the world through innovative clinical research. This concise handbook provides a practical «nuts and bolts» approach to the process of conducting clinical trials, identifying methods and techniques that can be replicated at other institutions and medical practices. Designed for investigators, research coordinators, CRO personnel, students, and others who have a desire to learn about clinical trials, this manual begins with an overview of the historical framework of clinical research, and leads the reader through a discussion of safety concerns and resulting regulations. Topics include Good Clinical Practice, informed consent, management of subject safety and data, as well as monitoring and reporting adverse events. Updated to reflect recent regulatory and clinical developments, the manual reviews the conduct of clinical trials research in an increasingly global context. This new edition has been further expanded to include: In-depth information on conducting clinical trials of medical devices and biologics The role and responsibilities of Institutional Review Boards, and Recent developments regarding subject privacy concerns and regulations. Ethical documents such as the Belmont Report and the Declaration of Helsinki are reviewed in relation to all aspects of clinical research, with a discussion of how researchers should apply the principles outlined in these important documents. This graphically appealing and eminently readable manual also provides sample forms and worksheets to facilitate data management and regulatory record retention; these can be modified and adapted for use at investigative sites.

MARRYING THE VIRGIN NANNYFrom the moment Maggie Shepherd picked up Jason’s baby son, he knew he’d found what he was looking for. He needed a mother for Brady; Maggie needed a place to call home. And taking her as his temporary wife was the perfect solution… THE NANNY AND MEWealthy lawyer Blake Decker thinks a nanny is just another employee. But he’s drawn to the irresistibly headstrong woman who insists he be more than a half-hearted father. As Casey coaxes Blake to open his heart to his niece, the nanny might just inspire him to open his heart to her as well… Two nannies plus two gorgeous bosses – romance that’s twice as heartwarming!

Dare to dream… these sparkling romances will make you laugh, cry and fall in love – again and again!Stacey loves children and travel – so accepting Luis’s offer to look after his adorable twin boys on the Spanish Riviera was a no-brainer. All widower Luis wants is to see his boys smile again, but Stacey’s zest for life is catching! She’s just the temporary nanny, but Luis now wants her to stay… as permanent nanny, mummy or… wife?