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Praise For Toxic People «From corporate America to the smallest business owner, this book should be mandatory reading because it provides toxic relief that will put money in your pocket and calm in your personality. A dose of this reading would enhance the success of business school students and smooth out a few bumps in a rocky marriage.» —Richard L. Labrum, Vice President, Wealth Management, Smith Barney «If you're just sick to death of those people who zap the energy right out of you, Marsha has the cure! In no-nonsense terms, she gives us the prescription for dealing with toxic people. She mixes in the right dosage of personal experience, humor, and practical advice to create a compelling message that is highly relevant in our personal and professional lives. I highly recommend this book to everyone interested in cleaning up toxic behaviors!» —John Ryan, Vice President, American Express «Marsha Petrie Sue is the Muhammad Ali of communicators. She can dance and look pretty, and she uses the entire ring, but she knows how and when to land a knockout punch. If you have bad relationships, you'll learn why. This is charm school with live ammunition!» —David Rawles, founder and President, Career Solutions, Inc. «Marsha Petrie Sue's 'take the bull by the horns' approach to self-realization and, if so chosen, self-improvement, is the antidote to today's wimpy leadership malaise. She takes readers by their collars, looks them straight in the eyes, and tells them in no uncertain terms that their key to both personal and professional happiness is attainable only through critical self-evaluation and the will to transcend their current situations.» —Randy O'Neill, Senior Vice President, Lancer Insurance Company «She has done it again! She gives us permission to 'sack the toxic people' who suck out our energy. Take Marsha's ticket to freedom: give yourself permission to send the toxic people on their not-so-merry way!» —Dr. Geoff Haw, Consultant, Sagacity Services, Australia «Marsha always finds a way to deliver the most difficult messages in a humorous way (this book is one example). You will be able to apply this book in everyday life and anywhere you encounter people!» —Tina Aguirre, Senior IT Manager, oil and energy company

The control of diseases in crops is still largely dominated by the use of fungicides, but with the increasing incidence of fungicide resistance, plus mounting concern for the environment resulting from excessive agrochemical use, the search for alternative, reliable methods of disease control is gaining momentum. The purpose of this important book is to examine the development and exploitation (or potential for exploitation) of a range of non-chemical approaches to disease control, with a focus on the need for a greater understanding of crop ecology as the basis for effective disease control in the field. Chapters in the book, written by international experts in the subject area, include coverage of: biological control methods host-plant resistance the exploitation of tolerance and the use of bacteriophages Carefully edited by Professor Dale Walters, widely respected for his work in the area of crop protection, Disease Control in Crops is an essential reference book for plant pathologists, microbiologists, plant and agricultural scientists and crop protection specialists, including those working within, and providing consultancy to, the agrochemical industries. Libraries in all universities and research establishments where biological sciences and agriculture are studied and taught should have copies of this timely publication on their shelves.

Discover how advances in mass spectrometry are fueling new discoveries across a broad range of research areas Electrospray and MALDI Mass Spectrometry brings both veteran practitioners and beginning scientists up to date with the most recent trends and findings in electrospray ionization and matrix-assisted laser desorption/ionization (MALDI) mass spectrometry. In particular, this Second Edition highlights how advances in electrospray and MALDI mass spectrometry are supporting important discoveries in new and emerging fields such as proteomics and metabolomics as well as in traditional areas of chemistry and physics research. Electrospray AND MALDI Mass Spectrometry, SECOND EDITION is divided into five parts: Part A, Fundamentals of ES, explains the fundamental phenomena underlying the electrospray process, including selectivity in ionization and inherent electrochemistry, and concludes with a chapter offering a comparative inventory of source hardware Part B, Fundamentals of MALDI, confronts ionization mechanisms, instrument development, and matrix selection, and includes a final chapter that explores the special application of MALDI to obtain two-dimensional images of spatial distributions of compounds on surfaces Part C, ES and MALDI Coupling to Mass Spectrometry Instrumentation, examines the coupling of these ionization techniques to various mass analyzers, including quadrupole ion trap, time-of-flight, Fourier transform ion cyclotron resonance, and ion mobility mass spectrometers Part D, Practical Aspects of ES and MALDI, investigates analytical issues including quantification, charge-state distributions, noncovalent interactions in solution that are preserved as gas-phase ions, and various means of ion excitation in preparation for tandem mass spectrometry, and offers a guide to the interpretation of even-electron mass spectra Part E, Biological Applications of ES and MALDI, examines the role of mass spectrometry in such areas as peptide and protein characterization, carbohydrate analysis, lipid analysis, and drug discovery Written by a team of leading experts, the book not only provides a critical review of the literature, but also presents key concepts in tutorial fashion to help readers take full advantage of the latest technological breakthroughs and applications. As a result, Electrospray and MALDI Mass Spectrometry will help researchers fully leverage the power of electrospray and MALDI mass spectrometry. The judicious compartmentalization of chapters, and the pedagogic presentation style throughout, render the book highly suitable for use as a text for graduate-level courses in advanced mass spectrometry.

Auf Einladung der Deutschen Forschungsgemeinschaft (DFG) fand am 9. und 10. Marz 2000 ein Rundgesprach uber heutige und kunftige Moglichkeiten des Biomonitoring in Arbeits- und Umweltmedizin statt. Das Biomonitoring hat nicht zuletzt durch die unmittelbare Umsetzung der Arbeitsergebnisse der Senatskommission zur Prufung gesundheitsschadlicher Arbeitsstoffe in geltendes Recht durch die deutsche Arbeitsschutzgesetzgebung in den letzten drei?ig Jahren in Deutschland ein hohes Niveau erreicht. Das vorliegende Buch fuhrt die Expertise verschiedener Fachdisziplinen von der Toxikologie, Arbeitsmedizin, Immunologie und Humangenetik bis hin zur Analytik und Epidemiologie zusammen. Hierbei wird die diagnostische Aussagekraft von zytogenetischen Parametern sowie von biochemischen und biologischen Effektmarkern fur die Pravention von schadstoffbedingter Erkrankungen ausfuhrlich erortert. Das gefuhrte Rundgesprach hat somit einen ersten Gedankenaustausch ermoglicht, aus dem sich kunftige Forschung entwickeln soll, um die fuhrende Rolle Deutschlands auf diesem wichtigen und sich dynamisch entwickelnden Forschungsgebiet zu halten.

While there are numerous books on heterocycles and natural products, this text fills the need for an up-to-date summary focusing on recently developed and improved synthetic methods for the preparation of the most important classes of lactones and lactams – all in one volume. Comprehensive in its coverage, this book also provides readers with a brief description of the occurrence and biological or pharmaceutical activity of the compounds, and each chapter deals with a certain class of lactones or lactames to enable quick access to the information needed. A valuable resource for organic chemists, biochemists and medicinal chemists in academia and industry wanting to learn about successful synthetic routes leading to important natural products and use this as inspiration for their own work in the lab.