Скачать книгу - The Genetic Basis of Haematological Cancers



Written by a team of international experts, this book provides an authoritative overview and practical guide to the molecular biology and genetic basis of haematologic cancers including leukemia. Focusing on the importance of cytogenetics and related assays, both as diagnostic tools and as a basis for translational research, this is an invaluable guide for basic and clinical researchers with an interest in medical genetics and haemato-oncology. The Genetic Basis of Haematological Cancers reviews the etiology and significance of genetic and epigenetic defects that occur in malignancies of the haematopoietic system. Some of these chromosomal and molecular aberrations are well established and already embedded in clinical management, while many others have only recently come to light as a result of advances in genomic technology and functional investigation. The book includes seven chapters written by clinical and academic leaders in the field, organised according to haematological malignancy sub-type. Each chapter includes a background on disease pathology and the genetic abnormalities most commonly associated with the condition. Authors present in-depth discussions outlining the biological significance of these lesions in pathogenesis and progression, and their use in diagnosis and monitoring response to therapy. The current or potential role of specific abnormalities as novel therapeutic targets is also discussed. There is also a full colour section containing original FISH, microarrays and immunostaining images.


Review. Benzene on the basis of the three-electron bond. Theory of three-electron bond in the four works with brief comments (review). 2016. Review. Benzene on the basis of the three-electron bond. Theory of three-electron bond in the four works with brief comments (review). 2016.

Автор: Volodymyr Bezverkhniy

Год издания: 

Using the concept of three-electron bond we can represent the actual electron structure of benzene and other molecules, explain specificity of the aromatic bond and calculate the delocalization energy. The aromatic bond is a three-electron bond in flat cyclic systems with a specific interaction of electrons through the cycle. In benzene formed a new type of chemical bonds – an aromatic bond, which has a multiplicity of more than 1.5 (1.66) http://vixra.org/author/bezverkhniy_volodymyr_dmytrovych


Horoscope for Cancers – 2018. Russian horoscope Horoscope for Cancers – 2018. Russian horoscope

Автор: Александр Невзоров

Год издания: 

Horoscopes for each Zodiac sign separately for 2018. Submitted by 7 Topics: Luck, Career, Vacation, Health, Sex, Love and Money. The stars predict that they expect signs in these areas and give advice. Sometimes paradoxical, but always correct based on the real situation. Horoscopes in verse for all signs of the zodiac are published by Alexander Nevzorov annually. Their readership is constantly expanding. Verses of horoscopes of excellent quality and like all.


The Methods and Scope of Genetics The Methods and Scope of Genetics

Автор: Bateson William

Год издания: 



The Scientific Basis of National Progress, Including that of Morality The Scientific Basis of National Progress, Including that of Morality

Автор: Gore George

Год издания: 



What is time? How and on the basis of what it is formed? What is time? How and on the basis of what it is formed?

Автор: Юрий Михайлович Низовцев

Год издания: 

You want to learn, from where undertakes, for what and how your own "now" is formed? Read further, and to you the mystery of own life will be revealed. Still about it only guessed. Now, having come to the key, you will understand for what you live and as it is possible to change the life. No fantasy will be compared to the paradoxes of reality opened and provided here.