Скачать книгу - Metabolic Syndrome. Underlying Mechanisms and Drug Therapies



This book provides a comprehensive overview of the development of metabolic syndrome, the underlying mechanisms and therapeutic strategies for drug development. The authors examine the context of underlying molecular pathways and integrated physiology, then expanding the discussion to diseases associated with metabolic syndrome. The development of drug therapies for these diseases and complications is extensively covered. The book offers a comprehensive and in-depth view of energy metabolism, metabolic tissues and pathways, molecular mechanism-based drug discovery and clinical implications.


The Cul-de-Sac Syndrome. Turning Around the Unsustainable American Dream The Cul-de-Sac Syndrome. Turning Around the Unsustainable American Dream

Автор: John Wasik F.

Год издания: 

An incisive look at the consequences of today's costly and damaging suburban lifestyle In The Cul-de-Sac Syndrome, Bloomberg News' John Wasik exposes the economic, cultural, environmental, and health problems underlying life in suburbia. Wasik provides powerful insights into how the U.S. suburban lifestyle has become unsustainable and what can be done to salvage it. His observations are firmly grounded in exclusive on-the-ground research, interviews with thought leaders, and the latest studies and statistics. The book Exposes the untold truths about suburban home ownership: green isn't always so green, life isn't cheaper after accounting for gas, water, and taxes, and modern suburban living isn't so idyllic considering the toll it takes on our health Includes exclusive research and analysis by experts in the field that debunks the many myths associated with suburban living Explores innovative solutions being developed in cities across the country The American Dream of moving further from a city to buy a bigger house and find better schools has become a costly nightmare. The Cul-de-Sac Syndrome examines why and what can be done.


The Jekyll and Hyde Syndrome. What to Do If Someone in Your Life Has a Dual Personality - or If You Do The Jekyll and Hyde Syndrome. What to Do If Someone in Your Life Has a Dual Personality - or If You Do

Автор: Beverly Engel

Год издания: 

Beverly Engel brings her expertise to this important examination of the Jekyll and Hyde Syndrome—the first book to address this abusive syndrome. She discusses the origins of the disorder, names its seven major manifestations, explains how to identify Jekyll and Hyde behavior in other people and in oneself, and outlines clear steps for how to heal Jekyll and Hyde tendencies for good.


Electron Flow in Organic Chemistry. A Decision-Based Guide to Organic Mechanisms Electron Flow in Organic Chemistry. A Decision-Based Guide to Organic Mechanisms

Автор: Paul Scudder H.

Год издания: 

Sets forth the analytical tools needed to solve key problems in organic chemistry With its acclaimed decision-based approach, Electron Flow in Organic Chemistry enables readers to develop the essential critical thinking skills needed to analyze and solve problems in organic chemistry, from the simple to complex. The author breaks down common mechanistic organic processes into their basic units to explain the core electron flow pathways that underlie these processes. Moreover, the text stresses the use of analytical tools such as flow charts, correlation matrices, and energy surfaces to enable readers new to organic chemistry to grasp the fundamentals at a much deeper level. This Second Edition of Electron Flow in Organic Chemistry has been thoroughly revised, reorganized, and streamlined in response to feedback from both students and instructors. Readers will find more flowcharts, correlation matrices, and algorithms that illustrate key decision-making processes step by step. There are new examples from the field of biochemistry, making the text more relevant to a broader range of readers in chemistry, biology, and medicine. This edition also offers three new chapters: Proton transfer and the principles of stability Important reaction archetypes Qualitative molecular orbital theory and pericyclic reactions The text's appendix features a variety of helpful tools, including a general bibliography, quick-reference charts and tables, pathway summaries, and a major decisions guide. With its emphasis on logical processes rather than memorization to solve mechanistic problems, this text gives readers a solid foundation to approach and solve any problem in organic chemistry.


Organic Reaction Mechanisms 2006. An annual survey covering the literature dated January to December 2006 Organic Reaction Mechanisms 2006. An annual survey covering the literature dated January to December 2006

Автор: A. Knipe C.

Год издания: 

Organic Reaction Mechanisms 2006 is the 42nd volume in this classical series. Every year, an experienced team of authors compiles these reviews, so that the reader can rely on a continuing quality of selection and presentation. Detailed author and subject indexes help the reader to find the information they are looking for. As a new service to the reader, all reaction mechanisms leading to stereospecific products are highlighted. This reflects the interest of synthetic organic chemists in such reactions and the pharmaceutical role of chiral molecules.


Organic Reaction Mechanisms 2007. An annual survey covering the literature dated January to December 2007 Organic Reaction Mechanisms 2007. An annual survey covering the literature dated January to December 2007

Автор: A. Knipe C.

Год издания: 

Organic Reaction Mechanisms 2007, the 43rd annual volume in this highly successful and unique series, surveys research on organic reaction mechanisms described in the available literature dated 2007. The following classes of organic reaction mechanisms are comprehensively reviewed: Reaction of Aldehydes and Ketones and their Derivatives Reactions of Carboxylic, Phosphoric, and Sulfonic Acids and their Derivatives Oxidation and Reduction Carbenes and Nitrenes Nucleophilic Aromatic Substitution Electrophilic Aromatic Substitution Carbocations Nucleophilic Aliphatic Substitution Carbanions and Electrophilic Aliphatic Substitution Elimination Reactions Polar Addition Reactions Cycloaddition Reactions Molecular Rearrangements An experienced team of authors compile these reviews every year, so that the reader can rely on a continuing quality of selection and presentation.